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MetabolomicsHuman umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical studies to clinical settings has necessitated the exploration o...

2023-07-25 | MTBLS7759 | MetaboLights
UnknownPhotoregulation of lipid metabolism in <i>Begonia</i>: synergistic effects of spectral composition and intensity on stress adaptation.
Not available
S-EPMC12855531 | biostudies-literature
UnknownLong-term strain improvements accumulate mutations in regulatory elements responsible for hyper-production of cellulolytic enzymes.
Not available
S-EPMC3610096 | biostudies-literature
UnknownBMP-2 and VEGF-A modRNAs in collagen scaffold synergistically drive bone repair through osteogenic and angiogenic pathways.
Not available
S-EPMC7815925 | biostudies-literature
UnknownCardiac Sympathetic Denervation for Termination of Ventricular Tachycardia Storm : A Multidisciplinary Case
Not available
S-EPMC12926055 | biostudies-literature
UnknownHsp90 Is a Novel Target Molecule of CDDO-Me in Inhibiting Proliferation of Ovarian Cancer Cells.
Not available
S-EPMC4489813 | biostudies-literature
TranscriptomicsSorted tumor RNA-seq of syngeneic murine mutant IDH1 ICC tumor model treated with IDH1 inhibitor against vehicle
IDH1 is the most commonly mutated metabolic gene across human cancers, with the highest mutational frequency observed in AML, glioma, chondrosarcoma, and intrahepatic cholangiocarcinoma. Mutations of the hot spot R132 codon alter the activity of the IDH1 enzyme, resulting in the NADPH-dependent conv...
ORGANISM(S): Mus musculus 
2021-11-23 | E-MTAB-11112 | biostudies-arrayexpress
UnknownSocioeconomic Disparities in Caregiver Burden Among Families of Older Patients With Cancer
Not available
S-EPMC12743282 | biostudies-literature
UnknowncircSLC4A7 accelerates stemness and progression of gastric cancer by interacting with HSP90 to activate NOTCH1 signaling pathway.
Not available
S-EPMC10359325 | biostudies-literature
UnknownGenome Mining and Metabolic Profiling Uncover Polycyclic Tetramate Macrolactams from Streptomyces koyangensis SCSIO 5802.
Not available
S-EPMC8399814 | biostudies-literature
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