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TranscriptomicsGenome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukemia
Although the 5-year survival of childhood Acute Lymphoblastic Leukemia (ALL) exceeds 80%, a group of patients presents poor prognosis due to early relapse. To date, treatment strategies are defined by cytogenetically-based subtype categorization. However, ALL patients without chromosomal translocati...
ORGANISM(S): Homo sapiens 
2012-11-07 | E-GEOD-39141 | biostudies-arrayexpress
TranscriptomicsDigoxin and its derivatives suppress Th17 cell differentiation by antagonizing RORγt activity
CD4+ T helper lymphocytes that express interleukin-17 (Th17 cells) have critical roles in mouse models of autoimmunity, and there is mounting evidence that they also influence inflammatory processes in humans. Genome-wide association studies in humans have linked genes involved in Th17 cell differe...
ORGANISM(S): Mus musculus 
2011-03-28 | E-GEOD-27241 | biostudies-arrayexpress
TranscriptomicsThe CURELUNG Project from the Epigenetics Side (Patients dataset)
Non-small cell lung cancer (NSCLC) is a very common solid tumor where only small advances in the reduction of relapse-free survival and overall survival have been accomplished. The issue is particularly critical for stage I patients where there are not available biomarkers, in the absence of detecta...
ORGANISM(S): Homo sapiens 
2013-10-03 | E-GEOD-39279 | biostudies-arrayexpress
GenomicsU219-array-CLL-00001000772 - samples
CLL Expression Array
EGAD00010000642 | EGA
GenomicsMYD88/TLR mutations in CLL
The Chronic Lymphocytic Leukemia (CLL) Genome Project aims to identify genetic alterations involved in the development and progression of the CLL, which are still unknown, with the objective of generating a comprehensive catalogue of genetic alterations in 500 independent tumours. The CLL Genome Pro...
EGAS00001000772 | EGA
GenomicsEGAS00000000092-ega-27092011 - samples
Recurrent Somatic Mutations in CLL
EGAD00001000044 | EGA
GenomicsEGAS00000000092-ega-20110419 2 - samples
Recurrent Somatic Mutations in CLL
EGAD00001000023 | EGA
GenomicsEGAD00010000280
CLL Expression array
EGAD00010000280 | EGA
GenomicsEGAD00010000238
CLL Expression array
EGAD00010000238 | EGA
Genomics20ExonArrays_EGAS00000000092 - samples
CLL Expression Array
EGAD00010000470 | EGA
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