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TranscriptomicsIntegrative analysis of DCE-MRI and gene expression profiles in construction of a gene classifier for assessment of hypoxia-related risk of chemoradiotherapy failure in cervical cancer
We have previously identified a prognostic 31-gene expression signature in locally advanced cervical cancer that is associated with tumor hypoxia and reflected by the dynamic contrast enhanced magnetic resonance (DCE-MR) image parameter ABrix. To bring the signature closer to clinical use, we here a...
ORGANISM(S): Homo sapiens 
2016-03-29 | E-GEOD-72723 | biostudies-arrayexpress
TranscriptomicsThe hypoxia marker pimonidazole reflects a transcriptional program associated with aggressive prostate cancer.
We aimed to investigate the transcriptional program associated with pimonidazole staining in prostate cancer. A pimonidazole gene signature was identified that showed positive correlation to Ki67 labeling index, indicating increased proliferation in pimonidazole positive tumors. A positive correlati...
ORGANISM(S): Homo sapiens 
2015-01-05 | E-GEOD-55935 | biostudies-arrayexpress
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