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ProteomicsRapid Histone Post-Translational Modification Analysis Using Alternative Proteases and Tandem Mass Tags (RIPUP)
Histone post-translational modifications (PTMs) alter chromatin dynamics and contribute to the regulation of gene expression in health and disease. Mass spectrometry-based analysis is the gold-standard for histone PTM analysis, but it remains constrained by inefficient sample preparation workflows r...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2026-06-20 | PXD073683 | Pride
Post-translational modifications Histones Proteases Lc-ms/ms 
MetabolomicsMetabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Thalassiosira pseudonana study)

Diatoms perform about 20% of photosynthesis on earth, play a crucial role in forming the base of the marine food web, and sequester anthropogenic carbon into the deep ocean through the biological pump. In some areas of the ocean, diatom growth is limited by the organic micronutrient cobalamin (vi...

2019-06-04 | MTBLS703 | MetaboLights
UnknownThe Stress-response protein prostate-associated gene 4, interacts with c-Jun and potentiates its transactivation.
Not available
S-EPMC4086653 | biostudies-literature
ProteomicsMass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancer

Filip Mundt, Sandeep Rajput, Shunqiang Li, Kelly Ruggles, Arshag D. Mooradian, Philipp Mertins, Michael A. Gillette, Karsten Krug, et al., Cancer Res. 2018 May 15;78(10):2732-2746. doi: 10.1158/0008-5472.CAN-17-1990.

Activation of phosphoinositide 3-kinase (PI3K) signaling is frequently obs...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-10-19 | MSV000083050 | MassIVE
UnknownFailures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun.
Not available
S-EPMC7819709 | biostudies-literature
TranscriptomicsGlycerol metabolism and PrfA activity in Listeria monocytogenes
Listeria monocytogenes is able to efficiently utilize glycerol as carbon source. In a defined minimal medium the growth rate is similar (during balanced growth) in presence of glycerol as in presence of glucose or cellobiose. Comparative transcriptome analyses of L. monocytogenes showed in the prese...
ORGANISM(S): Listeria monocytogenes 
2008-05-30 | E-GEOD-11459 | biostudies-arrayexpress
TranscriptomicsAbrupt scrib- vs. Abrupt and RasV12 (RasACT) scrib-, NotchICD (NACT) scrib- +/- JNK (Bsk) expression profiles
Drosophila mosaic eye-antennal discs from the listed genotypes generated using the MARCM system were dissected from 3rd instar larvae at day 5 after egg deposition. 20 pairs of discs for the Abrupt and scrib- + Abrupt samples and 50 pairs from FRT control, NACT scrib- +/- BskDN and RasACT scrib- +/-...
ORGANISM(S): Drosophila melanogaster 
2013-08-15 | E-GEOD-42938 | biostudies-arrayexpress
MetabolomicsHost-gut microbiota interactions shape parasite infections in farmed Atlantic salmon

Animals and their associated microbiota share long evolutionary histories. However, it is not always clear how host genotype and microbiota interact to affect phenotype. We applied a hologenomic approach to explore how host-microbiota interactions shape lifetime growth and parasite infection in f...

2024-01-24 | MTBLS8575 | MetaboLights
UnknownspatialLIBD: an R/Bioconductor package to visualize spatially-resolved transcriptomics data.
Not available
S-EPMC9188087 | biostudies-literature
MetabolomicsMetabolic consequences of cobalamin scarcity in diatoms as revealed through metabolomics (Navicula pelliculosa study)

Diatoms perform about 20% of photosynthesis on earth, play a crucial role in forming the base of the marine food web, and sequester anthropogenic carbon into the deep ocean through the biological pump. In some areas of the ocean, diatom growth is limited by the organic micronutrient cobalamin (vi...

2019-06-04 | MTBLS708 | MetaboLights
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