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ProteomicsProteome analysis of skeletal muscle samples from a porcine model of Duchenne muscular dystrophy treated by somatic gene editing
Duchenne muscular dystrophy (DMD) is caused by genetic deficiency of dystrophin and characterized by massive structural and functional changes of skeletal muscle tissue, leading to terminal muscle failure. In this project, proteomics data from skeletal muscle of a genetically engineered DMD pig mode...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2020-02-05 | PXD014893 | Pride
Porcine model Duchenne muscular dystrophy Somatic gene editing 
ProteomicsProteomic analysis of supernatant from NHP heart slices
Proteomic analysis was performed on secreted proteins from non human primate (NHP) heart slices (from Macaca fascicularis) in presence or absence of Cardiac progenitors (CPs) 48 h after radiofrequency ablation (RFA) to mimic tissue damage.
ORGANISM(S): Homo sapiens (Human) Macaca mulatta (Rhesus macaque) 
2022-02-28 | PXD019521 | Pride
Cardiac progenitors Heart Secretome Tissue remodeling 
ProteomicsAdult zebrafish cerebrospinal fluid (CSF) proteomics generated for ‘Brain defence by the extracellular matrix protein Cochlin
This dataset contains the proteomic profile of the adult zebrafish CSF sampled from the telencephalic ventricle towards understanding the secreted nature of the protein Cochlin and its contribution towards brain defense. Briefly, the vertebrate brain is protected from infection by tight barriers. Ho...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2026-09-12 | PXD081626 | Pride
Cerebrospinal fluid Bacterial immunity Zebrafish Cochlin 
UnknownReliability of high-quantity human brain organoids for modeling microcephaly, glioma invasion and drug screening.
Not available
S-EPMC11659410 | biostudies-literature
UnknownEndothelial Retargeting of AAV9 In Vivo.
Not available
S-EPMC8895123 | biostudies-literature
UnknownSomatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy.
Not available
S-EPMC7212064 | biostudies-literature
UnknownMigratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors.
Not available
S-EPMC9106586 | biostudies-literature
ProteomicsA precisely positioned MED12 activation helix stimulates CDK8 kinase activity
Chemical cross-linking coupled to mass spectrometry was used to study binary and ternary complexes involving cyclin-dependent kinase 8 (CDK8), cyclin-C, and subunit 12 of the Mediator complex (MED12). Cross-linking was performed using different cross-linking chemistries: (1) disuccinimidyl suberate ...
ORGANISM(S): Homo sapiens (Human) 
2020-01-16 | PXD015394 | Pride
Chemical cross-linking  dss  pdh  dmtmm  structural proteomics  mediator complex  kinase 
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