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TranscriptomicsHITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer.
We used a genome-wide approach (High-throughput sequencing of RNA isolated by crosslinking immunoprecipitation, or HITS-CLIP) to define direct miRNA-mRNA interactions in three breast cancer subtypes (estrogen receptor positive, Her2 amplified and triple negative). Focusing on steroid receptor signal...
ORGANISM(S): Homo sapiens 
2014-08-04 | E-GEOD-57855 | biostudies-arrayexpress
TranscriptomicsEstrogen receptor dynamics in diverse patient-derived luminal breast cancer xenografts
Primary breast cancer xenografts Two primary xenografts with different treatments
ORGANISM(S): Homo sapiens 
2013-02-24 | E-GEOD-36075 | biostudies-arrayexpress
TranscriptomicsImprovements to the HITS-CLIP protocol eliminate widespread mispriming artifacts.
High-throughput sequencing of RNA isolated by crosslinking immunoprecipitation (HITS-CLIP) allows for high resolution, genome-wide mapping of RNA-binding proteins. We found that substantial mispriming during reverse transcription results in the overrepresentation of sequences complementary to the pr...
ORGANISM(S): Homo sapiens 
2016-02-19 | E-GEOD-78059 | biostudies-arrayexpress
UnknownPhase Ia/b Study of Giredestrant ± Palbociclib and ± Luteinizing Hormone-Releasing Hormone Agonists in Estrogen Receptor-Positive, HER2-Negative, Locally Advanced/Metastatic Breast Cancer.
Not available
S-EPMC10870118 | biostudies-literature
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