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MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
UnknownA Chinese herbal decoction, reformulated from Kai-Xin-San, relieves the depression-like symptoms in stressed rats and induces neurogenesis in cultured neurons.
Not available
S-EPMC4957105 | biostudies-literature
TranscriptomicsRole of the histone demethylase KDM2B in hematopoietic homeostasis and malignancies [RNA-seq]
Development of the hematopoietic system is dynamically controlled by the interplay of transcriptional and epigenetic networks to determine cellular identity. Those networks are critical for homeostasis and frequently dysregulated in leukemias. We identified histone demethylase Kdm2b as a critical re...
ORGANISM(S): Mus musculus 
2016-02-22 | E-GEOD-70728 | biostudies-arrayexpress
GenomicsRole of the histone demethylase KDM2B in hematopoietic homeostasis and malignancies [ChIP-seq]
Development of the hematopoietic system is dynamically controlled by the interplay of transcriptional and epigenetic networks to determine cellular identity. Those networks are critical for homeostasis and frequently dysregulated in leukemias. We identified histone demethylase Kdm2b as a critical re...
ORGANISM(S): Homo sapiens 
2016-02-22 | E-GEOD-70624 | biostudies-arrayexpress
TranscriptomicsRole of the histone demethylase KDM2B in hematopoietic homeostasis and malignancies [human cell line gene expression]
Development of the hematopoietic system is dynamically controlled by the interplay of transcriptional and epigenetic networks to determine cellular identity. Those networks are critical for homeostasis and frequently dysregulated in leukemias. We identified histone demethylase Kdm2b as a critical re...
ORGANISM(S): Homo sapiens 
2016-02-22 | E-GEOD-74959 | biostudies-arrayexpress
TranscriptomicsRole of the histone demethylase KDM2B in hematopoietic homeostasis and malignancies [Kras background mouse gene expression]
Development of the hematopoietic system is dynamically controlled by the interplay of transcriptional and epigenetic networks to determine cellular identity. Those networks are critical for homeostasis and frequently dysregulated in leukemias. We identified histone demethylase Kdm2b as a critical re...
ORGANISM(S): Mus musculus 
2016-02-22 | E-GEOD-74960 | biostudies-arrayexpress
MetabolomicsA Combined Proteomic and Metabolomic Strategy for Allergens Characterization in Natural and Fermented Brassica napus Bee Pollen

Bee pollen is consumed for its nutritional and pharmacological benefits, but it also contains hazardous allergens which has not been identified. Here, we identified 2 potential allergens, glutaredoxin and oleosin-B2, in Brassica napus (B. napus) bee pollen using mass spectrometr...

2022-03-23 | MTBLS3950 | MetaboLights
Unknown2-Chloro-4-fluoro-N-phenyl-benzamide.
Not available
S-EPMC2977102 | biostudies-literature
Unknown3,6-Dichloro-N-(4-fluoro-phen-yl)picolinamide.
Not available
S-EPMC2977294 | biostudies-literature
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
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