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TranscriptomicsTranscription profiling of human peripheral blood mononuclear cells from diabetic children
Objective: We hypothesized that type 1 diabetes (T1D) is accompanied by changes in gene expression in peripheral blood mononuclear cells (PBMCs) due to dysregulation of adaptive and innate immunity, counterregulatory responses to immune dysregulation, insulin deficiency and hyperglycemia. Research D...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9006 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human stemic juvenile idiopathic arthritis, , systemic lupus erythematosus,, type I diabetes, metastatic melanoma, acute infections, or liver-transplant recipients undergoing immunosuppressive therapy (n = 37)
The analysis of patient blood transcriptional profiles offers a means to investigate the immunological mechanisms relevant to human diseases on a genome-wide scale. In addition, such studies provide a basis for the discovery of clinically relevant biomarker signatures. We designed a strategy for mic...
ORGANISM(S): Homo sapiens 
2008-10-04 | E-GEOD-11907 | biostudies-arrayexpress
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