Sort   by:  
 Page size 
TranscriptomicsAlterations in tumour necrosis factor signaling pathways associated with cytotoxicity and resistance to taxanes in tumour cells.
The taxanes are widely used in the treatment of breast and other cancers. While their cytotoxicity has been attributed to the induction of cell cycle arrest in mitosis through the stabilization of microtubules, we found that docetaxel promotes soluble tumor necrosis factor alpha (TNF-alpha producti...
ORGANISM(S): Homo sapiens 
2011-12-30 | E-GEOD-26129 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of anthracycline-resistant breast cancer cell lines
Drug resistance in breast cancer is the major obstacle to a successful outcome following chemotherapy treatment. While upregulation of multidrug resistance (MDR) genes is a key component of drug resistance in multiple cancers, the complexity and hierarchy of non-MDR driven drug resistance pathways a...
ORGANISM(S): Homo sapiens 
2014-01-24 | E-GEOD-54326 | biostudies-arrayexpress
Sort   by:  
 Page size