Sort   by:  
 Page size 
GenomicsHNF1A, UTX, H3K27me3 and H3K27ac ChIP-seq in wild-type and UTX- or HNF1A-deficient mouse pancreas
HNF1A and UTX are putative tumor suppressors in pancreatic cancer. In this study, we have combined mouse genetics, transcriptomics and genome binding studies to link HNF1A and UTX in a molecular mechanism that suppresses pancreatic cancer. In this session, we have profiled UTX, HNF1A, H3K27me3 and H...
ORGANISM(S): Mus musculus 
2019-12-20 | E-MTAB-7944 | biostudies-arrayexpress
TranscriptomicsRNA-seq of wild-type and Utx- or Hnf1a-deficient mouse pancreas
HNF1A and UTX are putative tumor suppressors in pancreatic cancer. In this study, we have combined mouse genetics, transcriptomics and genome binding studies to link HNF1A and UTX in a molecular mechanism that suppresses pancreatic cancer. In this session, we have determined the transcriptome of HNF...
ORGANISM(S): Mus musculus 
2019-12-20 | E-MTAB-7945 | biostudies-arrayexpress
GenomicsChIP-seq experiments of Estrogen Receptor Alpha (ERa) in the human breast cancer cell line T47D stably expressing GFP or neoGATA3
In this study, we investigated the functions of the most common GATA3 mutation (X308_Splice) that we called “neoGATA3”. Analysis of available molecular data from >3000 breast cancer patients revealed a dysregulation of the ERa-dependent transcriptional response in tumors carrying this mutations. ChI...
ORGANISM(S): Homo sapiens 
2020-06-29 | E-MTAB-9121 | biostudies-arrayexpress
Sort   by:  
 Page size