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Fibrosis, neurodegeneration, and cerebral angiomatosis (FINCA) (OMIM 618278) is a rare infantile-onset disease caused by variants in NHL repeat containing 2 (NHLRC2) gene. NHLRC2 is essential for mouse gastrulation (Hiltunen et al., 2022). Here, RNA sequencing was performed on four wild type (WT), f...
ORGANISM(S): Mus musculus 
Aging and sex have a strong influence on the functional capacity of the immune system. In general, the immune response in females is stronger than that in males, but there is little information about the effect of aging on this difference. To address this question, we performed a transcriptomic anal...
ORGANISM(S): Homo sapiens 
Here we performed a microarray experiment on samples of adherent cultures of Human Glioblastoma Cancer Stem Like Cells (NCH421K cell line) expressing a shRNA targeting the transcription factor ZEB1 (shZEB1) or a control shRNA targeting GFP 72 hours after lentiviral infection. This resulted in the g...
ORGANISM(S): Homo sapiens 
Hippocampal neuron cultures were prepared from neonatal C57BL/6N mice as previously described (Bading and Greenberg, Science, 1991). Cells were plated in dishes coated with Poly-D-Lysine (2mg/ml) and Laminin (10 µg/ml). Two days prior to harvesting, the medium was changed from NBA to transfection me...
ORGANISM(S): Mus musculus 
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