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TranscriptomicsEffect of tamoxifen on early gene expression in T47D cells
Tamoxifen is the treatment of choice in estrogen receptor alpha breast cancer patients. However, ~50% of ERM-NM-1-positive tumors exhibit intrinsic or rapidly acquire resistance to endocrine treatment, requiring chemotherapy. M-NM-^Yt has been difficult to predict de novo resistance to endocrine the...
ORGANISM(S): Homo sapiens 
2014-08-29 | E-GEOD-60878 | biostudies-arrayexpress
TranscriptomicsEffect of tamoxifen on early gene expression in MDA-MB-231 cells
Tamoxifen is the treatment of choice in estrogen receptor alpha breast cancer patients. However, ~50% of ERM-NM-1-positive tumors exhibit intrinsic or rapidly acquire resistance to endocrine treatment, requiring chemotherapy. M-NM-^Yt has been difficult to predict de novo resistance to endocrine the...
ORGANISM(S): Homo sapiens 
2014-08-29 | E-GEOD-60879 | biostudies-arrayexpress
TranscriptomicsTime-course effect of estradiol and ERa17p on Early Gene expression in T47D cells
ERM-NM-117p is a synthetic peptide corresponding to the sequence P295LMIKRSKKNSLALSLT311 of the estrogen receptor alpha (ERM-NM-1) and initially synthesized to mimic its calmodulin binding site. ERM-NM-117p was subsequently found to elicit estrogenic responses in E2-deprived ERM-NM-1-positive breast...
ORGANISM(S): Homo sapiens 
2012-07-30 | E-GEOD-39720 | biostudies-arrayexpress
TranscriptomicsTime-course effect of estradiol and ERa17p on Early Gene expression in MDA-MB-231 cells
ERM-NM-117p is a synthetic peptide corresponding to the sequence P295LMIKRSKKNSLALSLT311 of the estrogen receptor alpha (ERM-NM-1) and initially synthesized to mimic its calmodulin binding site. ERM-NM-117p was subsequently found to elicit estrogenic responses in E2-deprived ERM-NM-1-positive breast...
ORGANISM(S): Homo sapiens 
2012-07-30 | E-GEOD-39718 | biostudies-arrayexpress
TranscriptomicsTime-course effect of estradiol and ERa17p on Early Gene expression in SKBR3 cells
ERM-NM-117p is a synthetic peptide corresponding to the sequence P295LMIKRSKKNSLALSLT311 of the estrogen receptor alpha (ERM-NM-1) and initially synthesized to mimic its calmodulin binding site. ERM-NM-117p was subsequently found to elicit estrogenic responses in E2-deprived ERM-NM-1-positive breast...
ORGANISM(S): Homo sapiens 
2012-07-30 | E-GEOD-39719 | biostudies-arrayexpress
TranscriptomicsQuercetin effect on gene expression in HepG2 hepatocellular cancer cells
Quercetin is a flavonol modifying numerous cell processes with potent antiproliferative effects on cancer cell-lines. The aim of this study was to explore by gene-array analysis the effect of quercetin on cancer-related gene expression in HepG2 cells, followed by verification with RT-PCR and analysi...
ORGANISM(S): Homo sapiens 
2009-03-11 | E-GEOD-15162 | biostudies-arrayexpress
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