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OtherSirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity.
Data from ProteomeXchange, PXD ID: PXD001447. Experiment: SIRT4_MITO_MOCK1, file: SIRT4_MITO_MOCK1_05.mzml. Published as part of Cell. 2014 Dec 18;159(7):1615-25 . From the Abstract: {{i}} ... Here, we establish SIRT4 as a cellular lipoamidase that regulates the pyruvate dehydrogenase complex (PDH)...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320006423 | GPMDB
Resource Reanalysis 
UnknownA ZYG-12–dynein interaction at the nuclear envelope defines cytoskeletal architecture in theC. elegansgonad
Not available
S-JCBD-200902101 | bioimages
UnknownA Phase II Trial of Rivoceranib, an Oral Vascular Endothelial Growth Factor Receptor 2 Inhibitor, for Recurrent or Metastatic Adenoid Cystic Carcinoma.
Not available
S-EPMC10643996 | biostudies-literature
ProteomicsAP-MS analysis of sirtuin-4 interactions in human fibroblasts
Sirtuins (SIRTs) form a critical family of nicotinamide adenine dinucleotide (NAD)-dependent enzymes that govern genome regulation, metabolism, and aging. Despite conserved deacetylase domains, SIRTs4-7 have little to no deacetylase activity, and a robust catalytic activity for mitochondrial SIRT4 h...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-04 | MSV000079557 | MassIVE
MetabolomicsSuccinate accumulation drives ischaemia-reperfusion injury during organ transplantation
During heart transplantation, storage in cold preservation solution is thought to protect the organ by slowing metabolism; by providing osmotic support; and by minimising ischaemia-reperfusion (IR) injury upon transplantation into the recipient. Despite its widespread use, our understanding of the m...
2019-09-20 | MTBLS1085 | MetaboLights
UnknownA form of muscular dystrophy associated with pathogenic variants in JAG2.
Not available
S-EPMC8206160 | biostudies-literature
UnknownNational prospective cohort study of the burden of acute small bowel obstruction.
Not available
S-EPMC6551410 | biostudies-literature
UnknownOsimertinib or Platinum-Pemetrexed in EGFR T790M-Positive Lung Cancer.
Not available
S-EPMC6762027 | biostudies-literature
Genomicsena-DATASET-GoT2D/T2D-GENES-09-07-2016-02:03:47:226-1135 - samples
The GoT2D study includes ~2800 samples, half T2D cases and half T2D controls, of Northern European ancestry sequenced over 3 three technologies: deep whole exome sequencing, low-pass (4x) whole genome sequencing, and OMNI 2.5M genotyping. Samples were ascertained to be phenotypically "extreme" (e.g....
EGAD00001002247 | EGA
GenomicsImputation analysis file
This data set includes the following summary level data file used for the imputation data: imputation.sv.assoc.txt: results from single variant association analysis in imputed samples
EGAD00010001184 | EGA
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