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TranscriptomicsExpression data from pig BMDM treated with salmonella LPS
Mouse bone marrow-derived macrophages (BMDM) grown in macrophage colony-stimulating factor (CSF-1) have been used widely in studies of macrophage biology and the response to toll-like receptor agonists. We investigated whether similar cells could be derived from the domestic pig. Cultivation of pig ...
ORGANISM(S): Sus scrofa 
2011-08-31 | E-GEOD-30956 | biostudies-arrayexpress
TranscriptomicsPhenotype heterogeneity and maturation of alveolar macrophages in the domestic pig
The macrophages of the airways are the first line of innate immune defense against inhaled pathogens. We showed that pig bronchoalveolar cells are composed of an heterogeneous alveolar macrophage (AM) population. The adherent AM non-adherent produce more TNF when stimulated with bacterial compound a...
ORGANISM(S): Sus scrofa 
2014-02-01 | E-GEOD-52705 | biostudies-arrayexpress
TranscriptomicsThe impact of breed genotype and tissue compartment on the response of pig macrophages to lipopolysaccharide
The domestic pig (Sus scrofa) provides a large animal model for human innate immune responses and inflammation that is also economically important in its own right. Results: We demonstrate that macrophages can be harvested from 3 different compartments of the pig (lungs, blood and bone-marrow), cryo...
ORGANISM(S): Sus scrofa 
2013-04-13 | E-GEOD-45145 | biostudies-arrayexpress
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