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TranscriptomicsTranscriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils
The role of myeloid cells in supporting cancer growth is well established. Most work has focused on myeloid-derived suppressor cells (MDSC) that accumulate in tumor-bearing animals, but tumor-associated neutrophils (TAN) are also known to be capable of augmenting tumor growth. However, little is kno...
ORGANISM(S): Mus musculus 
2013-01-04 | E-GEOD-43254 | biostudies-arrayexpress
TranscriptomicsGene expression data from Arabidopsis C24 wild-type and ros1-1 seedlings.
We carried out a microarray experiment by using Affymetrix Arabidopsis ATH1 Genechips in order to identify genes that show reduced expression in ros1-1 plants. 2 samples examined: C24 wild-type and ros1-1 mutant (in C24 background).
ORGANISM(S): Arabidopsis thaliana 
2013-11-23 | E-GEOD-52669 | biostudies-arrayexpress
UnknownDeciphering the HLA-E immunopeptidome with mass spectrometry: an opportunity for universal mRNA vaccines and T-cell-directed immunotherapies.
Not available
S-EPMC11410602 | biostudies-literature
TranscriptomicsExpression data from rat tumors formed by 9L.EV or 9L.EGFRvIII cells
Analysis of rat tumor xenografts revealed genes that are upregulated in tumors expressing EGFRvIII 12 rats received intracranial injections of 9L cells expressing EGFRvIII or an empty vector control. Three weeks after implantation and subsequent growth, tumors were aseptically removed, processed fo...
ORGANISM(S): Rattus norvegicus 
2015-09-08 | E-GEOD-51147 | biostudies-arrayexpress
TranscriptomicsExpression data from human GBMs
Analysis of human glioblastoma multiforme tumors revealed genes that are upregulated in tumors expressing EGFRvIII compared to those expressing wild-type EGFR We examined gene expression in 52 primary GBM tumors, which were stratified based on the presence or absence of EGFRvIII expression using EGF...
ORGANISM(S): Homo sapiens 
2015-09-08 | E-GEOD-51062 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse BMAL-/- knockout at ZT14
Investigation of RNA transcript abundance in aortic tissue of BMAL-/- versus BMAL+/+ control mice at ZT14 Experiment Overall Design: One-way ANOVA design with Strain (BMAL-/- versus BMAL+/+) as the independent variable. Control group has five biological replicates, BMAL-/- group has four biological ...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3850 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse NPAS2 mutant at ZT14
Investigation of RNA transcript abundance in aortic tissue of NPAS2 mutant versus wild type mice at ZT14 Experiment Overall Design: One-way ANOVA design with Strain (NPAS mutant/WT) as the independent variable and five replicates in each group
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3849 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of atmbd4, atmbd6 and atmbd11 mutants of Arabidopsis thaliana
Methyl CpG Binding (MBD) proteins are a class of protein that binds with methylated DNA. In the model plant Arabidopsis thaliana there are 13 MBD proteins are there. To understand the gene regulation we performed microarray analysis of mutants of three genes (atmbd4, atmbd6 and atmbd11). Ten day old...
ORGANISM(S): Arabidopsis thaliana 
2014-07-09 | E-GEOD-59133 | biostudies-arrayexpress
GenomicsEpigenetic modifications induced by Blimp-1 regulate CD8+ T cell memory progression during acute virus infection
Blimp-1 regulates the overall accumulation of virus-specific CD8+ T cells during acute viral infections. Increased proliferation and survival of Blimp-1-deficient CD8+ T cells is promoted by persistent cytokine responsiveness, resulting from sustained expression of CD25 and CD27. Knockdown of thes...
ORGANISM(S): Mus musculus 
2013-10-10 | E-GEOD-48358 | biostudies-arrayexpress
GenomicsH3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-01-31 | E-GEOD-43922 | biostudies-arrayexpress
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