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TranscriptomicsGene expression changes in mouse embryonic fibroblasts (MEF cells) deficient for Ing1 and Gadd45a
ING1b and GADD45a are nuclear proteins involved in the regulation of cell growth, apoptosis and DNA repair. We found that ING1b and GADD45a physically and functionally interact in the epigenetic regulation of specific target genes. In order to study this interaction further, we analysed the transcri...
ORGANISM(S): Mus musculus 
2013-02-04 | E-GEOD-43318 | biostudies-arrayexpress
TranscriptomicsGene expression changes in HEK293T cells upon overexpression of ING1b and GADD45a
ING1b and GADD45a are nuclear proteins involved in the regulation of cell growth, apoptosis and DNA repair. We found that ING1b and GADD45a physically and functionally interact in the epigenetic regulation of specific target genes. In order to characterise the functional ING1b-GADD45a interaction, w...
ORGANISM(S): Homo sapiens 
2013-02-04 | E-GEOD-43317 | biostudies-arrayexpress
TranscriptomicsGadd45a and Ing1 interaction in epigenetic gene regulation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-02-04 | E-GEOD-43319 | biostudies-arrayexpress
ProteomicsPolyubiquitination analysis upon GSK3 inhibition in HeLa cell extracts
HeLa cell extracts with or without GSK3 enzyme inhibition were assayed using protein microarrays in order to detect GSK3-dependent changes in protein polyubiquitination. HeLa lysates in triplicates were supplemented with ubiquitin and incubated on protein microarrays (ProtoArray 5.0; Invitrogen) in ...
ORGANISM(S): Homo sapiens 
2014-05-15 | E-GEOD-50629 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Wnt3a-treated HeLa cells in G1 and G2/M phase
The early transcriptional response of HeLa cervical carcinoma cells to the canonical Wnt signalling pathway was investigated at two different cell cycle phases (G1 and G2/M) via microarray gene expression profiling. HeLa cells grown under standard conditions were treated for 3 h with either Control,...
ORGANISM(S): Homo sapiens 
2014-05-15 | E-GEOD-50248 | biostudies-arrayexpress
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