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TranscriptomicsTranscription profiling of mouse quiescent or dividing wild type and G3BP -/- MEFs
To determine whether the absence of G3BP alters the expression of genes involved in cellular proliferation and/or growth arrest, we performed a differential analysis of RNA transcripts isolated from quiescent or dividing wild type and G3BP -/- MEFs.
ORGANISM(S): Mus musculus 
2006-01-01 | E-MEXP-281 | biostudies-arrayexpress
TranscriptomicsCombined analysis of single cell RNA-Seq and ATAC-Seq data reveals regulatory toggles operating in native and iPS-derived retina
To improve the comparison of the developmental trajectories of native retina (NaR) and iPSC-derived 3D retinal aggregates(3D-RA) , we performed scRNA-Seq of murine NaR and 3D-RA at four matched stages of development: embryonic day (E)13 vs differentiation day (DD)13, postnatal day (P)0 vs DD21, P5 v...
ORGANISM(S): Mus musculus 
2021-06-30 | E-MTAB-9395 | biostudies-arrayexpress
TranscriptomicsATAC-Seq using native and iPSC-derived murine retina at three developmental stages.
To identify epigenetic programs underlying differentiation of mouse retina, we performed ATAC-Seq on bulk native retina (NaR) and iPSC-derived 3D retinal aggregates (3D-RA) at three matched stages of development: embryonic day (E)13 vs differentiation day (DD)13, postnatal day (P)0 vs DD21, and P5 v...
ORGANISM(S): Mus musculus 
2021-06-30 | E-MTAB-9440 | biostudies-arrayexpress
TranscriptomicsStranded Total RNA-seq of liver biopsy collected from Holstein Friesian cows
To explore potential functional genes related to milk production traits in cow, we performed total RNA-seq using liver biospy collected from 77 Holstein Friesian cows at postpartum 2 weeks.
ORGANISM(S): Bos taurus 
2021-07-09 | E-MTAB-9871 | biostudies-arrayexpress
TranscriptomicsATAC-seq of liver of a Holstein Friesian infant male.
We performed the assay for transposase-accessible chromatin using sequencing (ATAC-seq) on a liver sample collected from one Holstein Friesian healthy male at one month of age to profile open chromatin regions genome-wide to identify putative regulatory elements related to phenotype of interest.
ORGANISM(S): Bos taurus 
2021-07-09 | E-MTAB-9872 | biostudies-arrayexpress
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