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HM1, HP1a-/-, and HP1b-/- ESC transcriptomes were generated to determine whether depletion of these HP1 proteins influences gene and/or retroelement expression mRNA profiles of HP1a and HP1b Knockouts and its corresponding wildtype
ORGANISM(S): Mus musculus 
Transcription of endogenous retroviruses (ERVs) is inhibited by de novo DNA methylation during gametogenesis, a process initiated after birth in oocytes and at ~E15.5 in prospermatogonia. Earlier in germline development however, the genome, including most retrotransposons, is progressively demethyla...
ORGANISM(S): Mus musculus 
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