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TranscriptomicsIdentification of genes responsive to mild hyperthermia in human cervical squamous cell carcinoma HeLa cells
Hyperthermia (HT) is widely used to treat patients with various cancers. In general, HT elicits a wide spectrum of stress responses such as induction of heat shock proteins, protein aggregation and cell death in mammalian cells. Although many biological processes are affected by HT, the overall resp...
ORGANISM(S): Homo sapiens 
2013-01-24 | E-GEOD-43701 | biostudies-arrayexpress
TranscriptomicsIdentification of genes responsive to mild hyperthermia in human oral squamous cell carcinoma HSC-3 cells
Hyperthermia (HT) is widely used to treat patients with various cancers. In general, HT elicits a wide spectrum of stress responses, such as induction of heat shock proteins, protein aggregation and cell death in mammalian cells. Although many biological processes are affected by HT, the overall res...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-GEOD-43862 | biostudies-arrayexpress
UnknownGene expression profiling in HSF1-knockdown human oral squamous cell carcinoma HSC-3 cells
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-38058 | biostudies-other
TranscriptomicsIdentification of genes responsive to mild hyperthermia in human normal fibroblast OUMS-36 cells
Hyperthermia is widely used to treat patients with various cancers. Here, the effects of heat stress at 41M-BM-0C for 30 min (mild hyperthermia) on the gene expression in OUMS-36 human normal fibroblast cells were investigated using an Affymetrix GeneChip system. The cells were treated with mild hyp...
ORGANISM(S): Homo sapiens 
2012-07-12 | E-GEOD-39178 | biostudies-arrayexpress
TranscriptomicsIdentification of genes responsive to mild hyperthermia in human skin normal fibroblast Hs68 cells
Hyperthermia is widely used to treat patients with various cancers. Here, the effects of heat stress at 41M-BM-0C for 30 min (mild hyperthermia) on the gene expression in Hs68 human skin normal fibroblast cells were investigated using an Affymetrix GeneChip system. The cells were treated with mild h...
ORGANISM(S): Homo sapiens 
2012-07-12 | E-GEOD-39177 | biostudies-arrayexpress
TranscriptomicsIdentification of genes involved in cell differentiation of rat oral epithelial cell line ROE2
The use of in vitro cell culture systems has been of central importance for research of physiology, pharmacology, and toxicology, and functions at the cellular and molecular levels. We have developed an immortalized oral epithelial cell line ROE2 from fetal transgenic rats harboring temperature-sens...
ORGANISM(S): Rattus norvegicus 
2013-02-22 | E-GEOD-44560 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in HSF1-knockdown human oral squamous cell carcinoma HSC-3 cells
Heat shock transcription factor 1 (HSF1) is recognized as the major regulator of the heat shock transcriptional response, and also plays a central role in the cellular functions of cancer cells. Here, to identify the molecular mechanism by which HSF1 regulates the proliferation of cancer cells, comp...
ORGANISM(S): Homo sapiens 
2012-05-22 | E-GEOD-38058 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of the cell death induced by heat stress in DNA-PK-knockdown human cervical carcinoma HeLa cells
The objective of the present study is to investigate the role of DNA-PK inhibition in cell death induced by heat stress (44M-BM-0C, 60 min). Comparative gene expression analysis was performed with mock cells, negative control siRNA-treated cells and DNA-PK siRNA-treated cells. The expression of DNA-...
ORGANISM(S): Homo sapiens 
2012-07-12 | E-GEOD-39063 | biostudies-arrayexpress
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