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TranscriptomicsOviductal vs. ovarian epithelial transformation yields very different tumor phenotypes in Apc fl/fl;Pten fl/fl mice
We treated 6-8 week old mice that had floxed alleles of both Apc and Pten (for both alleles in each case) that also carry an Ovgp1-iCre-ERT2 transgene, with one of two treatments; a third group received neither treatment. The Ovgp1-iCre-ERT2 expresses Cre recombinase fused to a tamoxifen-inducible f...
ORGANISM(S): Mus musculus 
2016-08-25 | E-GEOD-80085 | biostudies-arrayexpress
Genomicsena-DATASET-RTL-11-03-2015-12:07:49:303-16 - samples
Whole genome sequencing was performed with DNA extracted from fresh-frozen tumor and normal material. Short insert DNA libraries were prepared with the TruSeq DNA PCRfree sample preparation kit (Illumina) for paired-end sequencing at a minimum read length of 2x100bp. Human DNA libraries were sequenc...
EGAD00001001273 | EGA
GenomicsComprehensive genomic profiles of small cell lung cancer
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. We found bi-allelic inactivation of TP53 and RB1 in nearly all the tumors analyzed, sometimes by complex genomic rearrangements. Two tumors with wild-type RB1 had evidence of chromothripsis leadi...
EGAS00001000925 | EGA
Genomicsena-DATASET-RTL-06-02-2015-14:59:15:066-180 - samples
RNA-sequencing (RNA-seq) was performed with RNA extracted from fresh-frozen human tumor tissue samples. cDNA libraries were prepared from poly-A selected RNA applying the Illumina TruSeq protocol for mRNA. The libraries were then sequenced with a 2 x 100bp paired-end protocol to a minimum mean cover...
EGAD00001001244 | EGA
GenomicsSCLC_SNP_6.0 - samples
SNP 6.0 arrays of small cell lung cancer
EGAD00010000558 | EGA
GenomicsDAC University of Cologne
Data Access Committee EGAC00001000064
EGAC00001000064 | EGA
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