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TranscriptomicsRNA-Seq of human lymph node stromal cells during the earliest phases of rheumatoid arthritis
Lymph node stromal cells (LNSCs) are an important lymphoid tissue cellular type that regulates the immune response and maintain peripheral tolerance. In rheumatoid arthritis, break of tolerance and formation of autoantibodies occurs years before arthritis. Studies in mice have shown lymph nodes acti...
ORGANISM(S): Homo sapiens 
2019-07-01 | E-MTAB-7897 | biostudies-arrayexpress
TranscriptomicsIllumina Humanmethylation450k array analysis in early synovial fibroblasts of RA patients before diagnosis
In the current study, we compared DNA methylation patterns using the Illumina 450k array technology between normal synovial fibroblasts and synovial fibroblasts from early (veRASF) and late stages of RA (estRASF) and transient, resolving arthritis (rSF). In doing so, we obtained a detailed view of...
ORGANISM(S): Homo sapiens 
2018-03-31 | E-MTAB-6581 | biostudies-arrayexpress
TranscriptomicsIllumina HumanmethylationEPIC array analysis in early synovial fibroblasts of RA patients before diagnosis
In the current study, we compared DNA methylation patterns using the Illumina 850k array technology between normal synovial fibroblasts and synovial fibroblasts from early (veRASF) and late stages of RA (estRASF) and transient, resolving arthritis (rSF). In doing so, we obtained a detailed view of...
ORGANISM(S): Homo sapiens 
2018-03-31 | E-MTAB-6582 | biostudies-arrayexpress
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