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MetabolomicsMetabolomic fingerprinting of bull spermatozoa for identification of fertility signature metabolites
The objective of the study was to identify the fertility-associated metabolites in bovine spermatozoa using liquid chromatography-mass spectrometry (LC-MS). Six Holstein Friesian crossbred bulls (three high-fertile and three low-fertile bulls) were the experimental animals. Sperm proteins were isola...
2021-12-07 | MTBLS1071 | MetaboLights
MetabolomicsDeciphering metabolomic alterations in seminal plasma of crossbred (Bos taurus X Bos indicus) bulls through comparative deep metabolomic analysis
The incidence of sub-fertility is higher in crossbred bulls compared to zebu bulls. In the present study, we analysed the metabolomic profile of seminal plasma from crossbred and zebu bulls and uncovered differentially expressed metabolites between these two breeds. Using a high-throughput LC-MS/MS-...
2021-12-22 | MTBLS1642 | MetaboLights
ProteomicsMetabolomics analysis highlights Yashtimadhu (Glycyrrhiza glabra L.) mediated neuroprotection in a rotenone-induced cellular model of Parkinsons disease
In the present study we carried out global and targeted metabolomics of differentiated IMR32 cells to study the neuroprotective mechanism of Yashtimadhu (Glycyrrhiza glabra L.) in rotenone induced cellular model of parkinsons disease. Our mass spectrometry data highlighted 2403 and 2934 aligned met...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-08-31 | MSV000088036 | MassIVE
MetabolomicsGNPS - Metabolomics analysis highlights Yashtimadhu (Glycyrrhiza glabra L.) mediated neuroprotection in a rotenone-induced cellular model of Parkinsons disease
In the present study we carried out global and targeted metabolomics of differentiated IMR32 cells to study the neuroprotective mechanism of Yashtimadhu (Glycyrrhiza glabra L.) in rotenone induced cellular model of parkinsons disease. Our mass spectrometry data highlighted 2403 and 2934 aligned met...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-08-31 | MSV000088036 | GNPS
MetabolomicsGNPS Global LC-MS/MS based metabolomic profiling of Triphala
Triphala is a herbal formulation widely used in Ayurveda as a rejuvenation and revitalization therapy. Its constitutes include a mixture of dried extracts from Phyllanthus emblica, Terminalia chebula, and Terminalia bellirica. In this study, we employed an LC-MS/MS based strategy for global profilin...
ORGANISM(S): Terminalia Chebula (ncbitaxon:155022) Terminalia Bellirica (ncbitaxon:155021) Phyllanthus Emblica (ncbitaxon:296036) 
2021-01-31 | MSV000086784 | GNPS
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