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GenomicsGlcNAcylation of histone H2B facilitates its monoubiquitination [Illumina Genome Analyzer data]
We report that histone GlcNAcylation of H2B S112 is a vital histone modification which facilitates histone monoubiquitination (ub). In a genome-wide analysis, H2B S112 GlcNAcylation sites were observed widely distributed over entire chromosomes including transcribed gene loci, together with co-local...
ORGANISM(S): Homo sapiens 
2011-10-27 | E-GEOD-33049 | biostudies-arrayexpress
TranscriptomicsGlobal survey of miRNA microarray of whole embryo, wild type vs estrogen receptor alpha knockout mice
To examine the effect of estrogen receptor alpha for the miRNA expression, total RNA extracted from whole embryos at E18.5 of wild type and Estrogen Receptor alpha knock-out mice Two group experiment (wild type and ER alpha KO)
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-13859 | biostudies-arrayexpress
TranscriptomicsGlobal survey of miRNA microarray of uterus, ovariectomized female mice with or without estrogen (E2) treatment
To examine the effect of E2 treatment for the miRNA expression, at 15 week old, female wiled type mice were ovariectomized, and after one week, estradiol (E2) was delivered at a concentration of 0.050 mg/kg body weight/day. 24 hours after chemical treatment, uteruses from mice treated with or withou...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-13858 | biostudies-arrayexpress
TranscriptomicsGlobal survey of miRNA profiles in the uterus and an estrogen receptor alpha knockout embryo
This SuperSeries is composed of the following subset Series: GSE13858: Global survey of miRNA microarray of uterus, ovariectomized female mice with or without estrogen (E2) treatment GSE13859: Global survey of miRNA microarray of whole embryo, wild type vs estrogen receptor alpha knockout mice Refer...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-14031 | biostudies-arrayexpress
TranscriptomicsGlobal survey of miRNA microarray of MCF-7 cells with or without estrogen (E2) treatment
To examine the effect of E2 treatment for the miRNA expression in human MCF-7 cells, MCF-7 cells were treated with or without E2 (100 nM) for 4 hr or 24 hr. Four group experiments; E2 (100 nM) treatment for 4 hr (MCF-7 E2 4h_1, MCF-7 E2 4h_2), vehicle (ethanol) treatment for 4 hr as Mock control ...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-16737 | biostudies-arrayexpress
TranscriptomicsRNA microarray of rat kidney treated with or without silicon nano-particles against ischemia reperfusion injury
RNA microarray was performed to evaluate the efficacy of silicon nano-particles on renal transcriptomes of rats against ischemia reperfusion injury. We compared the transcriptomes of ischemia reperfusion injury model rats with or without oral administration of silicon nano-particles. We also tried t...
ORGANISM(S): Rattus norvegicus 
2020-02-04 | E-MTAB-8687 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of wild type and p72 knock-out mice embryos
To examine the effect of DEAD-box RNA helicase subunits on the primary miRNAs processing by Drosha complex, we made knockout mice of p72, DEAD-box RNA helicase, a component of Drosha complex. And we compare the miRNA expression profiles derived from whole mice embryo between wild-type and p72 KO mic...
ORGANISM(S): Mus musculus 
2007-04-12 | E-MEXP-1052 | biostudies-arrayexpress
ProteomicsPRM of UMR106 pY-IP
UMR106 cells were untreated or treated with 5 mM Pi or 100 ng/ml FGF2 for 15 min. The lysates were digested with trypsin, and tyrosine-phosphorylated peptides were enriched by anti-phosphotyrosine antibody. Several selected peptides including FGFR1 with phosphorylated tyrosine residues were measured...
ORGANISM(S): Rattus Rattus (black Rat) 
2019-05-05 | PXD010791 | JPOST Repository
ProteomicsLFQ of UMR106 pY-IP
UMR106 cells were untreated or treated with 5 mM Pi or 100 ng/ml FGF2 for 15 min. The lysates were digested with trypsin, and tyrosine-phosphorylated peptides were enriched by anti-phosphotyrosine antibody and subjected to LC-MS/MS analysis. Raw data were directly analyzed against the SwissProt data...
ORGANISM(S): Rattus Rattus (black Rat) 
2019-05-05 | PXD010790 | JPOST Repository
ProteomicsDemonstration of a complementary approach for genetic diagnosis of inborn errors of immunity using proteogenomic analysis
Genetic diagnosis plays a central role in the clinical management of patients with inborn errors of immunity (IEI). We proposed a novel method for diagnosing IEI using PBMC proteomics integrated with targeted RNA sequencing, providing notable insights into the pathogenesis of IEI. Data-independent a...
ORGANISM(S): Homo Sapiens (human) 
2023-11-25 | PXD038352 | JPOST Repository
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