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TranscriptomicsGene expression from human prefrontal cortex (BA46)
Accumulating evidence suggests that mitochondrial dysfunction underlies the pathophysiology of bipolar disorder (BD) and schizophrenia (SZ). We performed large-scale DNA microarray analysis of postmortem brains of patients with BD or SZ, and examined expression patterns of mitochondria-related genes...
ORGANISM(S): Homo sapiens 
2008-09-03 | E-GEOD-12649 | biostudies-arrayexpress
TranscriptomicsTranscriptome patterns for Acute Cellular Rejection in Recipients with Recurrent Hepatitis C after Liver Transplantation
The histological evaluation of liver via biopsy remains as the standard for the diagnosis of both acute cellular rejection (ACR) and recurrent hepatitis C (RHC) after liver transplantation. Nevertheless, it is often difficult to diagnose ACR in HCV-positive recipients because of common co-existing a...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-13440 | biostudies-arrayexpress
GenomicsExome sequencing of autosomal recessive progressive external ophthalmoplegia (arPEO)

Progressive external ophthalmoplegia (PEO) is an inherited mitochondrial disease that follows either autosomal dominant or recessive forms of inheritance (adPEO or arPEO). AdPEO is a genetically heterogeneous disease and several genes including POLG1 and C10orf2/Twinkle have been id...

phs000392.v1.p1 | EGA
TranscriptomicsAffymetrix SNP array data for Japanese schizophrenia samples
Genome-wide association study (GWAS) was performed in 120 patient-parents trio samples from Japanese schizophrenia pedigrees ABSTRACT: Schizophrenia is a devastating neuropsychiatric disorder with genetically complex traits. Genetic variants should explain a considerable portion of the risk for sch...
ORGANISM(S): Homo sapiens 
2011-06-13 | E-GEOD-27923 | biostudies-arrayexpress
TranscriptomicsEvaluation of the whole genome amplification of bisulfite modified DNA
We compared genom-wide DNA methylation profiles between whole genome amplified bisufite-modified DNA and non-amplified DNA. 3 samples were bisulfite-converted, non-amplified DNA (technical triplicate). 6 samples were amplified with EpiTect® Whole Bisulfitome from 10ng or 50ng of bisulfite-converted ...
ORGANISM(S): Homo sapiens 
2015-07-22 | E-GEOD-39565 | biostudies-arrayexpress
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