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ProteomicsEffects of cis-regulatory elements on proteome
Background Genomic variations contribute to the phenotypic diversity of individuals. A number of polymorphisms in protein-coding regions that alter drug efficacy or lead to adverse reactions have been characterized; however, noncoding regions that affect drug responses are largely overlooked, except...
ORGANISM(S): Homo sapiens (Human) 
2025-04-17 | PXD060446 | Pride
Human Dia Hepatocyte Lc-ms/ms 
TranscriptomicsCapturing drug responses by quantitative promoter activity profiling
Quantitative analysis of cellular responses to signaling inhibitors. Total RNA obtained from MCF7 human breast cancer cell lines treated with 1uM gefitinib, 500nM U0126 or 10nM wortmannin for 6hr.
ORGANISM(S): Homo sapiens 
2013-07-10 | E-GEOD-48652 | biostudies-arrayexpress
TranscriptomicsAnalysis of the DNA methylome and transcriptome in granulopoiesis reveal timed changes and dynamic enhancer methylation [expression]
The study investigated the changes in DNA-methylation and gene expression during granulopoiesis. To this end CMP, GMP, PMC and PMN cell populations were isolated by FACS from bonemarrow from healty donors and analysed by CAGE as well as expression and DNA microarrays total RNA was isolated from CMP,...
ORGANISM(S): Homo sapiens 
2014-04-29 | E-GEOD-49883 | biostudies-arrayexpress
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