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TranscriptomicsGlobal expression analysis of HNF4alpha and HNFgamma-mediated transcriptional control
Hepatocyte nuclear factor-4α (HNF4α, NR2A1) is a nuclear receptor which has a critical role in hepatocyte differentiation and the maintenance of homeostasis in the adult liver. However, a detailed understanding of native HNF4α in the steady state remains to be elucidated. Here we report the native H...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-18973 | biostudies-arrayexpress
ProteomicsProteome analysis of BMPR2 mutation PASMCs
Proteome analysis of BMPR2 mutation PASMCs with or without PERK knockout under hypoxia.
ORGANISM(S): Mus Musculus (mouse) 
2021-07-03 | PXD020182 | JPOST Repository
GenomicsGenome-wide RING1B binding in Fbxl10 overexpressing 3T3-L1 cells at day 2 of differentiation
We analyzed RING1B binding regions in 3T3-L1 cell lines transduced with the retroviral vector for V5-tagged Fbxl10 or its dF-box mutant. RING1B ChIP-seq in empty, Fbxl10-1, and dF-box mutant vector transduced 3T3-L1 preadipocytes, in duplicate, and V5-Fbxl10 ChIP-seq in Fbxl10 overexpressing 3T3-L1 ...
ORGANISM(S): Mus musculus 
2015-03-04 | E-GEOD-64312 | biostudies-arrayexpress
TranscriptomicsExpression data from Fbxl10 overexpressing 3T3-L1 cells
Target genes of Fbxl10 during 3T3-L1 adipogenesis was analyzed 3T3-L1 cells overexpressing Fbxl10 using retrovirus system containing LTR promoter were differentiated and RNA was extracted at day 2 of differentiation
ORGANISM(S): Mus musculus 
2015-03-04 | E-GEOD-64154 | biostudies-arrayexpress
GenomicsProteomic analysis of native hepatocyte nuclear factor-4{alpha} (HNF4{alpha}) isoforms, phosphorylation status, and interactive cofactors.
Hepatocyte nuclear factor-4α (HNF4α, NR2A1) is a nuclear receptor which has a critical role in hepatocyte differentiation and the maintenance of homeostasis in the adult liver. However, a detailed understanding of native HNF4α in the steady state remains to be elucidated. Here we report the native H...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-18990 | biostudies-arrayexpress
GenomicsGenome-wide maps of HNF4a and HNF4g binding state in HepG2 cells.
Hepatocyte nuclear factor-4α (HNF4α, NR2A1) is a nuclear receptor which has a critical role in hepatocyte differentiation and the maintenance of homeostasis in the adult liver. However, a detailed understanding of native HNF4α in the steady state remains to be elucidated. Here we report the native H...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-18989 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis in ESET+/+ and ESET-/- thymocytes
Analysis of ESET deficient thymocytes at gene expression level. Each thymocyte developmental stage (preselected DP, postselected DP and CD4SP) was analysed. Total RNA obtained from isolated subpopulations of thymocytes from ESET+/+ and ESET-/- mice were analysed.
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-73951 | biostudies-arrayexpress
UnknownGenetic insights into ossification of the posterior longitudinal ligament of the spine.
Not available
S-EPMC10353864 | biostudies-literature
ProteomicsEffect of oncogenic transformation on metabolism 03
The expression levels of metabolic enzymes were estimated by MRM analysis with internal standard recombinant proteins. The analysis is performed in human diploid fibroblasts, TIG-3 cells and their derived cell lines (TS, TSM, and TSR). TIG-3 TS is immortalized cells by expressing hTERT and SV40 larg...
ORGANISM(S): Homo Sapiens (human) 
2016-12-03 | PXD004848 | JPOST Repository
ProteomicsTIG-3 quantification of metabolic enzymes set07
Absolute quantification of metabolic enzymes (core metabolic set) was carried out by MRM with internal standard recombinant proteins. Sample digests were labeled with mTRAQdelta0 and internal standard digests were labeled with mTRAQdelta4.
ORGANISM(S): Homo Sapiens (human) 
2016-12-03 | PXD004835 | JPOST Repository
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