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TranscriptomicsCharacterization of transcription patterns of bacteriophage fRSL1 genes during infection cycle.
fRSL1 is a jumbo myovirus stably and lytically infecting the phytopathogenic bacterium Ralstonia solanacearum. In this study, we investigate the infection cycle of fRSL1 and provide a genomic, proteomic and transcriptomic view of this phage. Its 231-kbp genome sequence showed many genes lacking dete...
ORGANISM(S): Ralstonia solanacearum 
2010-07-21 | E-GEOD-23017 | biostudies-arrayexpress
TranscriptomicsTransformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multi-step reactivation process
How malignant gliomas arise in a mature brain remains a mystery, hindering the development of preventive and therapeutic interventions. We previously showed that oligodendrocyte precursor cells (OPCs) can be transformed into glioma when mutations are introduced perinatally. However, adult OPCs rarel...
ORGANISM(S): Mus musculus 
2014-09-09 | E-GEOD-61282 | biostudies-arrayexpress
TranscriptomicsAn RNA-interacting protein network regulates pluripotency in mammalian primordial germ cells (Dazl knockdown)
Primordial germ cells (PGCs) are the embryonic precursors to egg and sperm. When removed from the embryonic gonad, PGCs can give rise to embryonic germ cell lines (EGs), pluripotent stem cells that display most of the characteristics of embryonic stem cells (ESCs) including the ability to form terat...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-39535 | biostudies-arrayexpress
TranscriptomicsAn RNA-interacting protein network regulates pluripotency in mammalian primordial germ cells (Dazl native RNA-IP)
Primordial germ cells (PGCs) are the embryonic precursors to egg and sperm. When removed from the embryonic gonad, PGCs can give rise to embryonic germ cell lines (EGs), pluripotent stem cells that display most of the characteristics of embryonic stem cells (ESCs) including the ability to form terat...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-39544 | biostudies-arrayexpress
TranscriptomicsAn RNA-interacting protein network regulates pluripotency in mammalian primordial germ cells (Dazl testis RNA-IP)
Primordial germ cells (PGCs) are the embryonic precursors to egg and sperm. When removed from the embryonic gonad, PGCs can give rise to embryonic germ cell lines (EGs), pluripotent stem cells that display most of the characteristics of embryonic stem cells (ESCs) including the ability to form terat...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-39545 | biostudies-arrayexpress
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