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UnknownThe Forward and Lateral Tilt Angle of the Neck and Trunk Measured by Three-Dimensional Gait and Motion Analysis as a Candidate for a Severity Index in Patients with Parkinson's Disease.
Not available
S-EPMC9504699 | biostudies-literature
TranscriptomicsExpression data from neutrophils from wild-type and Jdp2-/- mice
Jdp2 is a member of the AP-1 family and suppresses histone acetyltransferase activity. We used microarrays to examine the gene expression pattern of neutrophil form Jdp2-/- mice. Bone marrow CD11b+Ly6Clo Ly6G+ neutrophils form wild-type and Jdp2-/-mice were sorted by FACS, followed by RNA extraction...
ORGANISM(S): Mus musculus 
2012-11-30 | E-GEOD-42063 | biostudies-arrayexpress
UnknownDeletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice.
Not available
S-EPMC5470042 | biostudies-literature
UnknownDeciphering the inhibitory effects of trimetazidine on pulmonary hypertension development via decreasing fatty acid oxidation and promoting glucose oxidation.
Not available
S-EPMC11544210 | biostudies-literature
UnknownLoss of FCHSD1 leads to amelioration of chronic obstructive pulmonary disease.
Not available
S-EPMC8256015 | biostudies-literature
TranscriptomicsC/EBPa controls acquisition and maintenance of adult hematopoietic stem cell quiescence
In blood, the transcription factor C/EBPa is essential for myeloid differentiation and has been implicated in regulating self-renewal of fetal liver hematopoietic stem cells (HSCs). However, its function in adult HSCs is unknown. Here, using an inducible knockout model, we found that C/EBPa deficien...
ORGANISM(S): Mus musculus 
2012-11-14 | E-GEOD-42234 | biostudies-arrayexpress
TranscriptomicsA novel role of stem cell factor SALL4 as an oncofetal protein in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Treatment of HCC remains abysmal; discovery of novel pathways implicated in hepatocarcinogenesis is needed for more effective therapeutics. SALL4 is a stem cell factor essential for the maintenance of embry...
ORGANISM(S): Homo sapiens 
2012-02-22 | E-GEOD-35965 | biostudies-arrayexpress
TranscriptomicsCharacterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [short_hairpins_RNA-seq]
T-cell acute lymphoblastic leukemia (T-ALL) is an immature hematopoietic malignancy driven mainly by oncogenic activation of NOTCH1 signaling. In this study we abrogated the expression of JMJD3 (KDM6B) and UTX (KDM6A) H3K27me3 demethylases in human T-ALL lines and assayed for genome-wide expression ...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-56689 | biostudies-arrayexpress
TranscriptomicsTbr2 and Neurog2 occupancy and transcriptional profiling of control and Tbr2 knockout E14.5 cerebral cortices
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-09-08 | E-GEOD-63621 | biostudies-arrayexpress
TranscriptomicsLife span-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans
One of the most important issues in the study of aging is to discover compounds with longevity-promoting activity and to unravel their underlying mechanisms. Queen honey bees are continuously fed royal jelly (RJ), and they live more than 10 times longer than hive workers, derived from the same diplo...
ORGANISM(S): Caenorhabditis elegans 
2011-07-21 | E-GEOD-26094 | biostudies-arrayexpress
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