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UnknownObesity and Outcomes of Kawasaki Disease and COVID-19-Related Multisystem Inflammatory Syndrome in Children.
Not available
S-EPMC10709775 | biostudies-literature
GenomicsA SNF2 protein targets variable copy number repeats and thereby influences allele-specific expression
ATRX is an X-linked gene of the SWI/SNF family whose role in vivo is currently unknown. Mutations in ATRX cause syndromal mental retardation. ATRX binds to tandem repeat (TR) sequences both in heterochromatin (e.g. telomeres) and euchromatin. Genes associated with these TRs can be dysregulated when ...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-22162 | biostudies-arrayexpress
TranscriptomicsEffect of endoglin loss on embryoid bodies
Analysis of embryonic sten cell-derived embryoid bodies following endoglin knock out. Loss of endoglin leads to profound reduction of key hematopoietic regulators including SCL, LMO2, Gata2, and TGF-? signaling molecule ALK-1. Results provide insight into molecular mechanisms underlying hemangioblas...
ORGANISM(S): Mus musculus 
2011-05-16 | E-GEOD-29300 | biostudies-arrayexpress
TranscriptomicsTranscriptome of the maturing erythroblast
Understanding the pattern of gene expression and identifying the specific genes expressed during erythropoiesis is crucial for a synthesis of erythroid developmental biology. Here we have isolated four distinct populations of erythroblasts at successive erythropoietin-dependent stages of erythropoie...
ORGANISM(S): Homo sapiens 
2011-03-02 | E-GEOD-22552 | biostudies-arrayexpress
TranscriptomicsExpression data from diploid human pluripotent stem cells
Human pluripotent stem cells (hPSCs) tend to acquire chromosomal aberrations in culture, which may increase their tumorigenicity. However, the cellular mechanism(s) underlying these aberrations are largely unknown. Here we show that the DNA replication in aneuploid hPSCs is perturbed, resulting in h...
ORGANISM(S): Homo sapiens 
2015-11-12 | E-GEOD-64647 | biostudies-arrayexpress
TranscriptomicsThe transcriptional program controlled by Runx1 during early hematopoietic development (expression data)
Transcription factors have long been recognised as powerful regulators of mammalian development, yet it is largely unknown how individual key regulators operate within wider regulatory networks. Here we have used a combination of global gene expression and chromatin-immunoprecipitation approaches a...
ORGANISM(S): Mus musculus 
2012-05-29 | E-GEOD-29112 | biostudies-arrayexpress
TranscriptomicsRoles of mammalian Rap1 in TERT recruitment to chromatin, subtelomeric gene silencing and transcriptional regulation
Repressor-activator protein 1 (scRap1) is the major binding activity at Saccharomyces cerevisiae telomeres, with roles in telomere length regulation and establishment of subtelomeric silencing by recruiting the Sir proteins. scRap1 also acts as a transcription factor controlling the expression of ri...
ORGANISM(S): Mus musculus 
2010-07-10 | E-GEOD-19011 | biostudies-arrayexpress
UnknownPlasmacytoid Dendritic Cells Depletion and Elevation of IFN-γ Dependent Chemokines CXCL9 and CXCL10 in Children With Multisystem Inflammatory Syndrome.
Not available
S-EPMC8033149 | biostudies-literature
UnknownOutcomes of Chemoimmunotherapy Among Patients With Extensive-Stage Small Cell Lung Cancer According to Potential Clinical Trial Eligibility.
Not available
S-EPMC9958526 | biostudies-literature
TranscriptomicsAn RNA-interacting protein network regulates pluripotency in mammalian primordial germ cells (Dazl knockdown)
Primordial germ cells (PGCs) are the embryonic precursors to egg and sperm. When removed from the embryonic gonad, PGCs can give rise to embryonic germ cell lines (EGs), pluripotent stem cells that display most of the characteristics of embryonic stem cells (ESCs) including the ability to form terat...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-39535 | biostudies-arrayexpress
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