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TranscriptomicsTruncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line
Many thousand long non-coding (lnc) RNAs are mapped in the human genome. Time consuming studies using reverse genetic approaches by post-transcriptional knock-down or genetic modification of the locus demonstrated diverse biological functions for a few of these transcripts. The Human Gene Trap Mutan...
ORGANISM(S): Homo sapiens 
2015-12-22 | E-GEOD-71284 | biostudies-arrayexpress
TranscriptomicsComparison of haploid and diploid clones of KBM7 cancer cell line
The series were performed to study the changes in gene expression upon diploidization of KBM7 cancer (CML) cell line. The line can exist either as a clone with 24 chromosomes (nearly haploid) or with 48 chromosomes (nearly diploid). Gene expression patterns are largely ploidy-independent, as suggest...
ORGANISM(S): Homo sapiens 
2014-04-10 | E-GEOD-56465 | biostudies-arrayexpress
TranscriptomicsKBM7 genetrap mutant cells stimulated with TNF-alpha and IFN-gamma
Transcriptional response of KBM7 cells to IFN-gamma or TNF-alpha was investigated in control or cells with genetrap insertions in JAK2 or TNFRS1A, respectively. The experiment shows that, as expected, cells lacking JAK2 or TNFRS1A expression display a severly blunted response to the tested cytokines...
ORGANISM(S): Homo sapiens 
2013-08-09 | E-GEOD-48848 | biostudies-arrayexpress
GenomicsH3K9me3 ChIP-seq in KBM7 cells
We performed ChIP-seq to measure H3K9me3 levels in KBM7 cells
ORGANISM(S): Homo sapiens 
2015-05-28 | GSE60056 | GEO
GenomicsSimultaneous quantifications of protein-DNA contacts and transcriptomics in single cells (KBM7 data)
Simultaneous quantifications of protein-DNA contacts and transcriptomics in single cells (KBM7 data)
PRJNA509261 | ENA
TranscriptomicsIdentifying multi-locus chromatin contacts in human cells using tethered multiple 3C
Background: DNA in the nucleus of a living cell carries out its functions in the context of a complex, three-dimensional chromatin architecture. Several recently developed methods, each an extension of the chromatin conformation capture (3C) assay, have enabled the genome-wide profiling of chroma...
ORGANISM(S): Homo sapiens 
2015-04-29 | E-GEOD-60623 | biostudies-arrayexpress
GenomicsHomo sapiens isolate:KBM7
Homo sapiens isolate:KBM7 Raw sequence reads
PRJNA284009 | ENA
UnknownIdentification of Genes That Modulate Susceptibility to Formaldehyde and Imatinib by Functional Genomic Screening in Human Haploid KBM7 Cells.
Not available
S-EPMC4914802 | biostudies-literature
GenomicsYM155 selected genetrapped KBM7 cells
Mutagenized cell population of 100x10e6 KBM7 cells that were selected with 100 nM YM155 over 10 days of total treatment.
PRJEB6449 | ENA
TranscriptomicsKBM7 genetrap mutant cells stimulated with TNF-alpha and IFN-gamma
Transcriptional response of KBM7 cells to IFN-gamma or TNF-alpha was investigated in control or cells with genetrap insertions in JAK2 or TNFRS1A, respectively. The experiment shows that, as expected, cells lacking JAK2 or TNFRS1A expression display a severly blunted response to the tested cytokines...
ORGANISM(S): Homo sapiens 
2013-08-09 | GSE48848 | GEO
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