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TranscriptomicsYAP conveys an invasive phenotype to clear cell renal cell carcinoma cell lines via endothelin-2
To determine the biological mechanisms underlying the oncogenic properties of YAP in ccRCC the human ccRCC cell line MZ1774 was transduced with lentivirus containing a shRNA-cassette targeting YAP-mRNA. Expression profiles of MZ1774 YAP knockdown cells were compared to mock-transduced control cells....
ORGANISM(S): Homo sapiens 
2014-12-23 | E-GEOD-50053 | biostudies-arrayexpress
TranscriptomicsAcute venous hypertension induces local release of inflammatory cytokines and endothelial activation in humans
Background: Venous hypertension is often present in advanced and in acute decompensated heart failure (HF). However, it is unclear whether high intravenous pressure can cause alterations in homeostasis by promoting inflammation and endothelial cell (EC) activation. We used an experimental model of a...
ORGANISM(S): Homo sapiens 
2013-12-04 | E-GEOD-38783 | biostudies-arrayexpress
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