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Expression data from DC-induced Hopx-deficient and sufficient regulatory T cells after immunization

We found that Hopx is required for the function of DC-induced regulatory T cells in vivo. We used microarrays to identify relevant Hopx-targets in such cells after antigenic re-challenge in vivo. CD25/Foxp3 double positive DC-induced Hopx-deficient and sufficient regulatory T cells were FACS sorted ...

ORGANISM(S): Mus musculus

2010-08-29 | E-GEOD-23167 | biostudies-arrayexpress

Gene expression profiling: human CD8+CD45RO+ memory T cells in IL23 responsive and nonresponsive individuals

The interleukin-23 (IL-23) pathway plays a critical role in the pathogenesis of multiple chronic inflammatory disorders, however, inter-individual variability in IL-23-induced signal transduction in circulating human lymphocytes has not been well-defined. In this study, we observed marked, reproduci...

ORGANISM(S): Homo sapiens

2013-03-08 | E-GEOD-42051 | biostudies-arrayexpress

Achieving 1 ppm field homogeneity above 24 T: Application of differential mapping for shimming Keck and the Series Connected Hybrid magnets at the NHMFL.

Not available

S-EPMC6474693 | biostudies-literature

Transcription profiling of mouse IL-7Rhi/lo effector CD8 T cells on day 6/7 after LCMV armstrong infection

At the peak of the CD8 T cell response to acture viral and bacterial infections, expression of the Interleukin-7 Receptor (IL-7R) marks Memory Precursor Effector CD8 T Cells (MPECs) from other Short-Lived Effector CD8 T cells (SLECs), which are IL-7Rlo. This study was designed to determine the gene ...

ORGANISM(S): Mus musculus

2008-06-16 | E-GEOD-8678 | biostudies-arrayexpress

Expression data from effector CD4 T cells isolated from MRL/Faslpr mice.

MRL/Faslpr mice is a lupus prone strain that exhibits lupus disease features at 12-16 weeks of age, including high-titer circulating anti-DNA antibodies, splenomegaly, lymphadnopathy, skin lesions, and IgG deposits in the kidney. At 16-24 weeks of age, CD4+ B220- CD44+ T cells were sorted into three...

ORGANISM(S): Mus musculus

2010-03-18 | E-GEOD-20735 | biostudies-arrayexpress

Changes in Markers of T-Cell Senescence and Exhaustion With Atazanavir-, Raltegravir-, and Darunavir-Based Initial Antiviral Therapy: ACTG 5260s.

Not available

S-EPMC4978379 | biostudies-literature

Integrative genomic analysis identifies clinically relevant subtypes of head and neck cancer characterized by hypoxia, T-cell infiltration, and EMT

Current classification of head and neck squamous cell carcinomas (HNSCC) based on anatomic site and clinical stage fails to capture biologic heterogeneity or adequately inform treatment. Here we use consensus clustering on 371 HNSCC in three cohorts, including a new cohort of 134 patients with locor...

ORGANISM(S): Homo sapiens

2015-03-04 | E-GEOD-40774 | biostudies-arrayexpress

Selective loss of 5hmC links to A-T Purkinje cell vulnerability

PRJNA260387 | ENA

Pathogenic Role of MIF Receptor (CD74) Expressing T cells in Inflammatory Arthritis

PRJNA1390592 | ENA

T-cell TGF-β signaling abrogation restricts medulloblastoma progression.

Not available

S-EPMC4143044 | biostudies-literature