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GenomicsPRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies [ChIP-seq]
The polycomb repressive complex 2 (PRC2) exerts oncogenic effects in many tumour types1. However, loss-of-function mutations in PRC2 components occur in a subset of haematopoietic malignancies, suggesting that this complex plays a dichotomous and poorly understood role in cancer2,3. Here we provide ...
ORGANISM(S): Homo sapiens 
2014-10-21 | E-GEOD-62499 | biostudies-arrayexpress
TranscriptomicsPRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies [expression array]
The polycomb repressive complex 2 (PRC2) exerts oncogenic effects in many tumour types1. However, loss-of-function mutations in PRC2 components occur in a subset of haematopoietic malignancies, sug- gesting that this complex plays a dichotomous and poorly understood role in cancer2,3. Here we provid...
ORGANISM(S): Homo sapiens 
2014-10-21 | E-GEOD-62500 | biostudies-arrayexpress
UnknownRevised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome: an international consensus recommendation.
Not available
S-EPMC8354850 | biostudies-literature
UnknownComparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Not available
S-EPMC7808408 | biostudies-literature
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