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ProteomicsDIA proteomic profiling of psoriasis: pharmacological rescue in an imiquimod-induced mouse model and CRISPR knockout human keratinocytes
This dataset contains quantitative, bottom-up DIA proteomics data generated as part of a larger study entitled "AI-Guided CRISPR Screen Reveals Repurposed Drugs as Topical Psoriasis Therapeutics," and is organized into two complementary sub-studies.Sub-study 1 – Pharmacological Rescue in a Mouse Pso...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-05-21 | PXD071833 | Pride
TranscriptomicsIntegrating phenotypic and expression profiles to map arsenic response networks
The parent S. cerevisiae strain, BY4741, and specific gene deletions of the parent S.cerevisiae strain BY4741 were treated with 100uM NaAsO2 (AsIII) for 2h and compared to the untreated counterpart (yap1Î? vs. yap1Î? 2h 100uM AsIII, cad1Î? vs. cad1Î? 2h 100uMAsIII, rpn4Î? vs. rpn4Î? 2h 100uM AsIII, ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-05 | E-GEOD-1798 | biostudies-arrayexpress
UnknownNew Genome Assemblies for Poeciliidae: A Foundation for Adaptation Studies.
Not available
S-EPMC12204701 | biostudies-literature
TranscriptomicsLong non-coding RNAs regulate adipogenesis (Affymetrix)
Adipogenesis involves the regulation of hundreds of genes by several well-studied proteins, but the role of long, noncoding RNAs in this process has not been defined. We track the regulation of hundreds of lncRNAs during adipocyte differentiation, and find several that are essential for this proces...
ORGANISM(S): Mus musculus 
2013-02-15 | E-GEOD-29897 | biostudies-arrayexpress
TranscriptomicsGene expression data from human metastatic melanoma tumors that may predict response to RAF265
To determine how mutation of BRAF affected the response to RAF265, we utilized a tumor orthotopic implant model of early passage melanoma tumors in nude mice from a series of 17 patients with advanced metastatic Tumor growth was compared between RAF265 treatment (40 mg/kg, QD) and diluent control gr...
ORGANISM(S): Homo sapiens 
2012-05-01 | E-GEOD-30812 | biostudies-arrayexpress
GenomicsExome_array_250K
Argentine samples using 250K
EGAD00010001075 | EGA
GenomicsPopulation Structure and Genetic Diversity in Argentinean populations
Argentina was one of the last places peopled when humans entered the Americas. Its earliest archeological sites are dated from 13,000 years BP, and throughout its history the region has exhibited broad cultural diversity, involving both hunter-gatherer and agro-pastoral societies, different linguist...
EGAS00001001663 | EGA
GenomicsDAC for study Population Structure and Genetic Diversity in Argentinean populations
Data Access Committee EGAC00001000426
EGAC00001000426 | EGA
TranscriptomicsLong non-coding RNAs regulate adipogenesis (Illumina RNA-Seq)
Adipogenesis involves the regulation of hundreds of genes by several well-studied proteins, but the role of long, noncoding RNAs in this process has not been defined. We track the regulation of hundreds of lncRNAs during adipocyte differentiation, and find several that are essential for this proces...
ORGANISM(S): Mus musculus 
2013-02-15 | E-GEOD-29898 | biostudies-arrayexpress
UnknownPotent antitumor activity of cabozantinib, a c-MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model.
Not available
S-EPMC4323738 | biostudies-literature
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