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TranscriptomicsMicroarray skeletal muscle PGC-1alpha-/- - beta f/f/Mlc1fCre mice
Title: Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity Abstract: Evidence is emerging that the PGC-1 coactivators serve a critical role in skeletal muscle metabolism, function, and disease. Mice with total PGC-1 defic...
ORGANISM(S): Mus musculus 
2010-12-01 | E-GEOD-23365 | biostudies-arrayexpress
TranscriptomicsMapping of nascent RNA in MLL2 F/F and FC/FC MEF cells
Global Run-On has been performed in MLL2 F/F and FC/FC MEF cells. The aim of the experiment is to test how the lack of MLL2 affects nascent RNA transcription. Four samples were analyzed - 2 independent replicates. The experiments were performed using immortalized mouse embryonic fibroblasts (MEF) in...
ORGANISM(S): Mus musculus 
2016-04-13 | E-GEOD-73126 | biostudies-arrayexpress
TranscriptomicsGenome wide profiling of the RNAPII, γH2AX, H3K4Me1, H3K4M2 and H3K4Me3 in MLL2 F/F and FC/FC MEF cells
We investigated the RNAPII and γH2AX occupancy genome wide by ChIP-Seq in MLL2 F/F and FC/FC80 MEF cells. We found that a week after MLL2 excision (FC/FC cells), a group of genes present higher levels of γH2AX and RNAPII near the TSS, as compared to the control (F/F cells). H3K4Me1, H3K4M2 and H3...
ORGANISM(S): Mus musculus 
2016-04-13 | E-GEOD-73124 | biostudies-arrayexpress
GenomicsMus musculus
Microarray skeletal muscle PGC-1alpha-/- - beta f/f/Mlc1fCre mice
PRJNA131245 | ENA
TranscriptomicsMicroarray of cardiac biventricle from PGC-1a-/-bf/f/MerCre mice
The following abstract from the submitted manuscript describes the major findings of this work. The metabolic development of high energy-utilizing organs such as the heart involves mitochondrial proliferation at birth followed by a maturation process during the postnatal period. Conditional gene tar...
ORGANISM(S): Mus musculus 
2014-01-13 | E-GEOD-43798 | biostudies-arrayexpress
MetabolomicsMetabolomic profiling of Fraxinus excelsior genotypes tolerant or susceptible to ash dieback disease reveals changes in iridoid glycosides
European common ash, Fraxinus excelsior L., is currently threatened by Ash dieback (ADB) caused by the fungus, Hymenoscyphus fraxineus. To detect and identify metabolites that may be products of pathways important in contributing to resistance against H. fraxineus we performed untargeted metabolomic...
2016-11-09 | MTBLS372 | MetaboLights
UnknownComplete genome sequence for the thermoacidophilic archaeon Sulfuracidifex (f. Sulfolobus) metallicus DSM 6482.
Not available
S-EPMC10793343 | biostudies-literature
TranscriptomicsRNA-seq of monocytes from a variety of mouse tissues
We investigated the transcriptomes of monocytes in a variety of mouse tissue. Monocytes were were identified as CD45+ Lin(CD3ε, TCR-β, CD19, B220, NK1.1, Ter119, Siglec F, Ly6G)- CD11b+ Ly6Chi CD64- MHCII- and their RNA was sequenced on the Illumina HiSeq2500PE
ORGANISM(S): Mus musculus 
2021-02-05 | E-MTAB-10039 | biostudies-arrayexpress
UnknownDrosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
Not available
S-EPMC4426361 | biostudies-literature
UnknownAn eye on equity: faricimab-driven health equity improvements in diabetic macular oedema using a distributional cost-effectiveness analysis from a UK societal perspective.
Not available
S-EPMC11226444 | biostudies-literature
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