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TranscriptomicsmRNA expression profiling in the spinal nerve ligation model of neuropathic pain in rats
Expression profiling of L4 and L5 Dorsal Root Ganglion (DRG) in the spinal nerve ligation model of neuropathic pain. The goal of the study was to identify genes involved in neuropathic pain This series of samples comprises of contralateral and ipsilateral L4 and L5 DRG tissue collected 4 weeks afte...
ORGANISM(S): Rattus norvegicus 
2011-10-17 | E-GEOD-24982 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling in the Lungs of Patients with Chronic Obstructive Pulmonary Disease (COPD) and Lung Cancer
COPD is a common and disabling lung disease for which very few therapeutic options are currently available. We reasoned that global gene expression profiling of COPD lungs could reveal previously unidentified disease pathways for potential therapeutic interventions. Forty-eight human lung samples we...
ORGANISM(S): Homo sapiens 
2007-11-09 | E-GEOD-8500 | biostudies-arrayexpress
GenomicsChIP-seq defined genome-wide map of TGFbeta/SMAD4 targets: implications with clinical outcome of ovarian cancer patients
Deregulation of the transforming growth factor-? (TGF?) signaling pathway in epithelial ovarian cancer has been reported, but the precise mechanism underlying disrupted TGF? signaling in the disease remains unclear. We performed chromatin immunoprecipitation followed by sequencing (ChIP-seq) to inve...
ORGANISM(S): Homo sapiens 
2011-06-30 | E-GEOD-27526 | biostudies-arrayexpress
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