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ProteomicsKinome profiling of venetoclax-resistant wild type and NRAS-G12C MOLM-14 cells
Despite efficacy of FLT3 and BCL2 inhibition in acute myeloid leukemia (AML), relapse limits survival. Mutation status and AML monocytic differentiation are implicated in resistance. On-treatment tumor evolution may select for genetically distinct clones or shifts in differentiation not resolvable ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD068585 | Pride
Venetoclax Gilteritinib Kinase Inhibitor Bead Aml 
ProteomicsKinome profiling of osteosarcoma patient-derived xenograft TT2 treated with palbociclib
Osteosarcoma (OS) is the most common primary bone cancer in adolescents, young adults (AYA), and children, with up to 25% of patients developing metastatic disease, primarily in the lungs. Despite survival rates being >70% for localized tumors, patients with metastatic OS have <30% survival due to l...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD069093 | Pride
Kinase Inhibitor Bead Pi3k Cdk4/6 Mtor 
TranscriptomicsmRNA expression profiling in the spinal nerve ligation model of neuropathic pain in rats
Expression profiling of L4 and L5 Dorsal Root Ganglion (DRG) in the spinal nerve ligation model of neuropathic pain. The goal of the study was to identify genes involved in neuropathic pain This series of samples comprises of contralateral and ipsilateral L4 and L5 DRG tissue collected 4 weeks afte...
ORGANISM(S): Rattus norvegicus 
2011-10-17 | E-GEOD-24982 | biostudies-arrayexpress
MetabolomicsSARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals
Viruses manipulate cellular metabolism and macromolecule recycling processes like autophagy. Dysregulated metabolism might lead to excessive inflammatory and autoimmune responses as observed in severe and long COVID-19 patients. Here we show that SARS-CoV-2 modulates cellular metabolism and reduces ...
2021-06-11 | MTBLS2840 | MetaboLights
UnknownBaseline Features and Reasons for Nonparticipation in the Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM) Study, a Colorectal Cancer Screening Trial.
Not available
S-EPMC10336619 | biostudies-literature
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