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TranscriptomicsTranscriptomic and metabolic responses of mycorrhizal roots to nitrogen patches under field conditions
Arbuscular mycorrhizal (AM) fungi contribute to plant nutrient uptake in systems managed with reduced fertilizer inputs such as organic agriculture and natural ecosystems by extending the effective size of the rhizosphere and delivering mineral. Connecting the molecular study of the AM symbiosis wi...
ORGANISM(S): Solanum lycopersicum 
2011-06-29 | E-GEOD-30270 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver after Con, Veh, Dex treatments reveals glucocorticoid signalling synchronizes the liver transcriptiome
Mouse liver RNA was extracted using Trizol (Invitrogen) and Qiagen RNeasy kits. RNA was checked with an Agilent Bioanalyzer for evidence of sub-genomic DNA and degradation. Targets were produced using standard Affymetrix protocols. Each sample represents data from a single mouse liver.
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-564 | biostudies-arrayexpress
TranscriptomicsDifferential production of Type I IFN determines the reciprocal levels of IL-10 and proinflammatory cytokines produced by C57BL/6 and BALB/c macrophages
Pattern recognition receptors (PRR) detect microbial products and induce cytokines which shape the immunological response. Interleukin-12 (IL-12), tumor necrosis factor alpha (TNF-α) and IL-1β are proinflammatory cytokines which can be essential for resistance against infection, but if produced at...
ORGANISM(S): Mus musculus 
2016-09-07 | E-GEOD-79809 | biostudies-arrayexpress
TranscriptomicsThe E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity cancer.
The androgen receptor (AR) plays a central role in the development of castration resistant prostate cancer (CRPC). Here, we demonstrate that the ubiquitin ligase Siah2 targets a select pool of NCOR1-bound, transcriptionally inactive AR for ubiquitination dependent degradation, thereby promoting the ...
ORGANISM(S): Homo sapiens 
2013-02-15 | E-GEOD-44319 | biostudies-arrayexpress
TranscriptomicsA mechanism for triggering cell differentiation in Arabidopsis
To determine whether IYO is not only necessary but also sufficient to activate transcription of developmental programs, we compared the transcriptome of shoot apices from 35S::IYO-GFP plants to that of 35S::GFP plants at the time of inflorescence emergence. Our results strongly suggest that IYO acti...
ORGANISM(S): Arabidopsis thaliana 
2011-07-08 | E-GEOD-22817 | biostudies-arrayexpress
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