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TranscriptomicsGene expression profiling in psoriatic lesional and non-lesional skin [Set 1]
To explore the psoriasis phenotype, we characterize gene expression in lesional and non-lesional skin from psoriasis patients. We extracted total RNA from 5mm punch biopsies taken from 14 psoriatic patients. From each patient, we obtained two biopsies, one from a lesion and the other from non-lesion...
ORGANISM(S): Homo sapiens 
2013-01-28 | E-GEOD-34248 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in psoriatic lesional and non-lesional skin [Set 2]
To explore the psoriasis phenotype and pathways involved in psoriasis, we characterized gene expression in lesional and non-lesional skin from psoriasis patients. From each of the 24 psoriasis patients, we obtained two biopsies, one from a lesion and the other from non-lesional skin in the same gene...
ORGANISM(S): Homo sapiens 
2013-01-28 | E-GEOD-41662 | biostudies-arrayexpress
TranscriptomicsRe-analysis by microarray using cDNA target of samples from psoriasis patients enrolled in an etanercept trial
cDNA and cRNA hybridization technologies have different, probe-specific sensitivities. We used samples from an etanercept trial (GSE11903) to explore in a real-life setting the uniqueness of each platform. We obtained total RNA for a subset of the samples in GSE11903 from Jim Krueger and generated e...
ORGANISM(S): Homo sapiens 
2013-01-28 | E-GEOD-41663 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in psoriatic lesional and non-lesional skin [brodalumab treatment]
To explore the psoriasis phenotype and pathways involved in psoriasis, we characterized gene expression in lesional and non-lesional skin from psoriasis patients. Furthermore, we explored the effects of various doses of brodalumab on lesional skin over time. From each of the 25 psoriasis patients, w...
ORGANISM(S): Homo sapiens 
2014-03-31 | E-GEOD-53552 | biostudies-arrayexpress
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