Ketogenesis - OmicsDI

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CDK4-driven ketogenesis rewires histone modification to promote leukemia

How ketogenic metabolites affect tumorigenesis, and whether ketone metabolism becomes deregulated in cancer cells, remain incompletely understood. Using T-cell acute lymphoblastic leukemia (T-ALL) as a model, we demonstrate that the ketone body β-hydroxybutyrate (BHB) is elevated in cancer cells ...

2026-01-28 | MTBLS13793 | MetaboLights

Circadian clock controls rhythms in ketogenesis by interfering with PPARa transcriptional network

PRJNA873076 | ENA

Ketogenesis promotes leukemia development by inhibiting ferroptosis in leukemic stem cells [ATAC-Seq]

PRJNA1441601 | ENA

Hepatocyte-specific Sirt6 deficiency impairs ketogenesis.

Not available

S-EPMC6364758 | biostudies-literature

Ketogenesis promotes leukemia development by inhibiting ferroptosis in leukemic stem cells [RNA-Seq]

PRJNA1441599 | ENA

PPARa regulates ER-lipid droplet protein Calsyntenin-3b to promote ketogenesis in hepatocytes

PRJNA1224734 | ENA