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PARP inhibitors as single agents and in combination therapy: the most promising treatment strategies in clinical trials for BRCA-mutant ovarian and triple-negative breast cancers.
Not available
S-EPMC9296104
|
biostudies-literature
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Selective CDK4/6 Inhibitors: Biologic Outcomes, Determinants of Sensitivity, Mechanisms of Resistance, Combinatorial Approaches, and Pharmacodynamic Biomarkers.
Not available
S-EPMC7306922
|
biostudies-literature
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Estrogen receptor alpha is cell cycle-regulated and regulates the cell cycle in a ligand-dependent fashion.
Not available
S-EPMC4934046
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biostudies-literature
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Low molecular weight cyclin E overexpression shortens mitosis, leading to chromosome missegregation and centrosome amplification.
Not available
S-EPMC2888821
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biostudies-literature
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Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells.
Not available
S-EPMC105379
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biostudies-literature
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The serine protease inhibitor elafin maintains normal growth control by opposing the mitogenic effects of neutrophil elastase.
Not available
S-EPMC4362782
|
biostudies-literature
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Low-Molecular-Weight Cyclin E in Human Cancer: Cellular Consequences and Opportunities for Targeted Therapies.
Not available
S-EPMC6168358
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biostudies-literature
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Cyclin E deregulation impairs mitotic progression through premature activation of Cdc25C.
Not available
S-EPMC2946214
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biostudies-literature
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Specific, reversible G1 arrest by UCN-01 in vivo provides cytostatic protection of normal cells against cytotoxic chemotherapy in breast cancer.
Not available
S-EPMC7078276
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biostudies-literature
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Staurosporine is chemoprotective by inducing G1 arrest in a Chk1- and pRb-dependent manner.
Not available
S-EPMC3786379
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