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TranscriptomicsRNASeq of HEK293 suspension cells treated with a 72 h hyperthermic shift to 40°C versus untreated (37°C) controls
Experiment aimed at understanding the cellular mechanisms leading to increased extracellular vesicle concentration under hyperthermic conditions. Human embryonic kidney (HEK293) cells were cultured 48 h under normal conditions (37°C/140 rpm/5% CO2) before being subjected to a 72 h, 40°C temperature ...
ORGANISM(S): Homo sapiens 
2023-08-10 | E-MTAB-13273 | biostudies-arrayexpress
TranscriptomicsRNASeq of HEK293 suspension cell-derived sEVs treated with a 72 h hyperthermic shift to 40°C versus untreated (37°C) controls
Experiment aimed at understanding the compositional changes of small extracellular vesicles (sEVs) derived from cells grown under hyperthermic conditions. Human embryonic kidney (HEK293) cells were cultured 48 h under normal conditions (37°C/140 rpm/5% CO2) before being subjected to a 72 h, 40°C tem...
ORGANISM(S): Homo sapiens 
2023-08-18 | E-MTAB-13285 | biostudies-arrayexpress
TranscriptomicsRNA-seq of miRNA and piRNA of Exosomes and whole cell lysates from CHO-K1 Cell Cultures at different growth phases
In biopharmaceutical production, Chinese hamster ovary (CHO) cells derived from Cricetulus griseus remain the most commonly used host cell for recombinant protein production, especially antibodies. Over the last decade in-depth multi-omics characterization of these CHO cells provided data for extens...
ORGANISM(S): Cricetulus griseus 
2021-01-18 | E-MTAB-9894 | biostudies-arrayexpress
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