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TranscriptomicsKDM5B focuses H3K4 methylation near promoters and enhancers during embryonic stem cell self-renewal and differentiation [RNA-Seq]
Pluripotency of embryonic stem (ES) cells is controlled in part by chromatin-modifying factors that regulate histone H3 lysine 4 (H3K4) methylation. However, it remains unclear how H3K4 demethylation contributes to ES cell function. Here, we show that KDM5B, which demethylates lysine 4 of histone H3...
ORGANISM(S): Mus musculus 
2014-01-27 | E-GEOD-53090 | biostudies-arrayexpress
GenomicsKDM5B focuses H3K4 methylation near promoters and enhancers during embryonic stem cell self-renewal and differentiation [ChIP-Seq]
Pluripotency of embryonic stem (ES) cells is controlled in part by chromatin-modifying factors that regulate histone H3 lysine 4 (H3K4) methylation. However, it remains unclear how H3K4 demethylation contributes to ES cell function. Here, we show that KDM5B, which demethylates lysine 4 of histone H3...
ORGANISM(S): Mus musculus 
2014-01-27 | E-GEOD-53087 | biostudies-arrayexpress
TranscriptomicsExtended self-renewal and accelerated reprogramming in the absence of Kdm5b [RNA-Seq]
ES cell pluripotency is thought to be regulated in part by H3K4 methylation. However, it is unclear how H3K4 demethylation contributes to ES cell function and participates in iPS cell reprogramming. Here, we show that KDM5B, which demethylates H3K4, is important for ES cell differentiation, and pres...
ORGANISM(S): Mus musculus 
2013-10-14 | E-GEOD-47124 | biostudies-arrayexpress
GenomicsExtended self-renewal and accelerated reprogramming in the absence of Kdm5b [ChIP-Seq]
ES cell pluripotency is thought to be regulated in part by H3K4 methylation. However, it is unclear how H3K4 demethylation contributes to ES cell function and participates in iPS cell reprogramming. Here, we show that KDM5B, which demethylates H3K4, is important for ES cell differentiation, and pres...
ORGANISM(S): Mus musculus 
2013-10-14 | E-GEOD-47123 | biostudies-arrayexpress
TranscriptomicsExtended self-renewal and accelerated reprogramming in the absence of Kdm5b
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-10-14 | E-GEOD-46893 | biostudies-arrayexpress
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