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TranscriptomicsExpression data from mouse embryonic fibroblasts
In addition to transcriptional regulation, mRNA degradation critically contributes to gene expression as shown by various biological analysis. The CCR4-NOT complex serves as a major deadenylase that initiates mRNA degradation. We used microarrays to identify CCR4-NOT targets by searching for genes s...
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-67418 | biostudies-arrayexpress
TranscriptomicsRoles of mRNA decay in liver development
mRNA decay machineries play important roles in various biological events. Among them, Cnot deadenylase complex has a critical function to trigger mRNA decay. To understand roles of the complex in liver development, we compare RNA expression between control and Cnot complex-deficient liver.
ORGANISM(S): Mus musculus 
2019-02-01 | E-MTAB-7182 | biostudies-arrayexpress
TranscriptomicsEffects of PMA on exon usage of HL60, THP-1, and U937 cells
Myeloid leukemia cell lines HL60, THP-1, and U937 undergo macrophage-like differentiation after treatment with phorbol ester. To explore genes whose exon usage was altered during macrophage differentiation, we compared exome of PMA-treated (differentated) and vehicle-treated (undifferentiated) myelo...
ORGANISM(S): Homo sapiens 
2013-09-25 | E-GEOD-20567 | biostudies-arrayexpress
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