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TranscriptomicsNetwork Analysis Reveals a Novel Role for the AP-1 Transcription Factor JUNB in Classical and Alternative Macrophage Activation
Bone marrow-derived macrophages were generated from wild type and Junb knockout mice and tested for their responses to LPS treatment. Independent replicate wells from wild type and knockout bone marrow-derived macrophages were mock-treated or LPS-treated. RNA was isolated at 4 h post-treatment, ampl...
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-50542 | biostudies-arrayexpress
TranscriptomicsTrimming of sequence reads alters RNA-Seq gene expression estimates
Background High-throughput RNA-Sequencing (RNA-Seq) has become the preferred technique for studying gene expression differences between biological samples and for discovering novel isoforms, though the techniques to analyze the resulting data are still immature. One pre-processing step that is widel...
ORGANISM(S): Drosophila melanogaster 
2016-02-25 | E-GEOD-72884 | biostudies-arrayexpress
TranscriptomicsThe microRNA bantam regulates a developmental transition in epithelial cells that restricts sensory dendrite growth
Microarray profiling of GFP-marked epithelial cells isolated by FACS from 1st and 3rd instar wild type and mutant Drosophila larvae. Multiple independent replicates collected for each population/timepoint combination. RNA isolated and amplified from FACS-sorted populations. Hybridized as two-color...
ORGANISM(S): Drosophila melanogaster 
2014-08-04 | E-GEOD-50540 | biostudies-arrayexpress
TranscriptomicsInterferon signaling during early experimental malaria infection
Microarray profiling of whole blood of immunodeficient mouse strains at 24h after infection with Plasmodium chabaudi. Multiple independent replicates collected for each knockout. RNA isolated and amplified. Hybridized as two-color experiment against a common pooled reference.
ORGANISM(S): Mus musculus 
2012-11-19 | E-GEOD-23565 | biostudies-arrayexpress
TranscriptomicsNK cells and immune memory
Microarray profiling of adoptively transferred GFP-marked NK cells during MCMV infection in C57BL/6 mice Multiple independent replicates were collected per time point. NK cells were isolated from spleens of mice by flow cytometry. RNA isolated, amplified, and hybridized as two-color experiment aga...
ORGANISM(S): Mus musculus 
2011-02-11 | E-GEOD-25672 | biostudies-arrayexpress
TranscriptomicsDelineation of diverse macrophage activation programs in response to intracellular parasites and cytokines
To provide a global perspective on the relationships between macrophage activation programs and to understand how certain pathogens circumvent them, we used transcriptional profiling by genome wide microarray analysis to compare the responses of mouse macrophages following exposure to the intracellu...
ORGANISM(S): Mus musculus 
2010-04-13 | E-GEOD-20087 | biostudies-arrayexpress
TranscriptomicsDistinct functional programming of human fetal and adult monocytes [set 2]
Microarray profiling of unstimulated and IFNg-stimulated human fetal and adult bone marrow classical monocytes Classical monocytes were stimulated or no with IFNg for 4 hours, sort purified, RNA isolated, and amplified. 4 of each sample was collected and used
ORGANISM(S): Homo sapiens 
2014-05-02 | E-GEOD-54817 | biostudies-arrayexpress
TranscriptomicsDistinct functional programming of human fetal and adult monocytes [set 1]
Microarray profiling of unstimulated human fetal and adult bone marrow classical monocytes Classical monocytes were sort purified, RNA isolated, and amplified. 4 of each sample was collected and used
ORGANISM(S): Homo sapiens 
2014-05-02 | E-GEOD-54668 | biostudies-arrayexpress
UnknownSMARCA4 biology in alveolar rhabdomyosarcoma.
Not available
S-EPMC9985831 | biostudies-literature
UnknownNon-chemotherapy adjuvant agents in TP53 mutant Ewing sarcoma.
Not available
S-EPMC10474113 | biostudies-literature
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