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MetabolomicsMetabolomic analysis reveals a differential adaptation process of the larval stages of Anisakis simplex to the host environment

Anisakis simplex are parasitic nematodes that cause anisakiasis. The possibility of infection with this parasite is through consumption of raw or undercooked fish products. A. simplex infections are often misdiagnosed, especially in subclinical cases that do not present with typ...

2023-07-08 | MTBLS6458 | MetaboLights
MetabolomicsEnergy-stress-mediated AMPK activation inhibits ferroptosis

Energy stress depletes ATP and induces cell death. Here we identify an unexpected inhibitory role of energy stress on ferroptosis, a form of regulated cell death induced by iron-dependent lipid peroxidation. We found that ferroptotic cell death and lipid peroxidation can be inhibited by treatment...

2023-01-31 | MTBLS1399 | MetaboLights
UnknownSimultaneous Computation of Dynamical and Equilibrium Information Using a Weighted Ensemble of Trajectories.
Not available
S-EPMC4168800 | biostudies-literature
GenomicsExamination of hepatic SREBP-2 binding using ChIP-Seq
Sterol regulatory element binding proteins (SREBPs) are key transcriptional regulators of lipid metabolism. To define functional differences between the three mammalian SREBPs we are using genome-wide ChIP-seq with isoform-specific antibodies and chromatin from select tissues of mice challenged with...
ORGANISM(S): Mus musculus 
2011-03-22 | E-GEOD-28082 | biostudies-arrayexpress
UnknownDiagnosis prediction of tumours of unknown origin using ImmunoGenius, a machine learning-based expert system for immunohistochemistry profile interpretation.
Not available
S-EPMC7953791 | biostudies-literature
UnknownCaffeoyl-Prolyl-Histidine Amide Inhibits Fyn and Alleviates Atopic Dermatitis-Like Phenotypes via Suppression of NF-κB Activation.
Not available
S-EPMC7582254 | biostudies-literature
UnknownClinical and Microbiological Characteristics of Hospital-Acquired Methicillin-Resistant Staphylococcus aureus Bacteremia Caused by a Community-Associated PVL-Negative Strain.
Not available
S-EPMC8527597 | biostudies-literature
GenomicsUsf1, a Suppressor of the Circadian Clock Mutant, Reveals the Nature of the DNA-binding of the CLOCK:BMAL1 complex in mice
Genetic and molecular approaches have been critical for elucidating the mechanism of the mammalian circadian clock. Here, we demonstrate that the ClockM-NM-^T19 mutant behavioral phenotype is significantly modified by mouse strain genetic background. We map a suppressor of the ClockM-NM-^T19 mutatio...
ORGANISM(S): Mus musculus 
2013-04-21 | E-GEOD-44609 | biostudies-arrayexpress
UnknownEmergence of multidrug-resistant Salmonella enterica serovar typhi in Korea.
Not available
S-EPMC525459 | biostudies-literature
UnknownProgrammable protein circuits in living cells.
Not available
S-EPMC7176481 | biostudies-literature
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