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Genomicswhole exome sequencing of Korean hepatocellular carcinomas
Data Access Committee EGAC00001000329
EGAC00001000329 | EGA
TranscriptomicsSmad3 regulates the miR-200 family in gastric cancer
To find potential microRNA links between Smad3 and E-cadherin, we characterized the microRNA profiles of two gastric cancer cell lines: SNU484-LPCX, which does not express Smad3, and SNU484-Smad3, in which Smad3 is overexpressed. We found that miR-200 families, among other differentially expressed m...
ORGANISM(S): Homo sapiens 
2011-09-14 | E-GEOD-27977 | biostudies-arrayexpress
Genomics97dd9532-0482-4bf1-ad1d-fb976b8ed7ea - samples
This dataset contains whole-genome sequencing data files from colon organoid cultures, which were mutated using CRISPR-Cas9 for specific genes (APC, KRAS, TP53 and SMAD4) to generate in vitro transformed cancer cells. After introducing each mutation, the resulting cultures were subjected to whole-ge...
EGAD00001002719 | EGA
TranscriptomicsIntergrated expression profiling and ChIP-SEQ analyses of ChREBP-mediated glucose response network (expression data only)
We identified ChREBP-binding regions from the DNA of human hepatocellular targets as well as previously-known targets Total RNA from hepG2 cell line
ORGANISM(S): Homo sapiens 
2010-06-16 | E-GEOD-22074 | biostudies-arrayexpress
GenomicsWhole genome sequencing of colon organoid cultures with artificially induced oncogenic mutations
Using the CRISPR-Cas9 genome editing system, various oncogenic mutations were introduced in the genome of normal adult stem cells derived from the colon. The resulting clonal cultures were subjected to whole genome sequencing. In addition, the cultures were transplanted in a mouse and the resulting ...
EGAS00001001969 | EGA
GenomicsDivision of Biomedical Genetics UMC Utrecht
Data Access Committee EGAC00001000432
EGAC00001000432 | EGA
GenomicsThese are from Korean HCC samples with exome sequencing
Hepatic resection is the most curative treatment option for early-stage hepatocellular carcinoma, but is associated with a high recurrence rate, which exceeds 50% at 5 years after surgery. Understanding the genetic basis of hepatocellular carcinoma at surgically curable stages may enable the identif...
EGAS00001000604 | EGA
Genomicsena-DATASET-asan-ccgd-27-09-2019-00:22:21:191-59 - samples
231 HCC exome sequencing with Sureselect 50Mb
EGAD00001005361 | EGA
TranscriptomicsCytoScanHD array Data for 15 normal, 15 primary colorectal carcinomas and their 15 matched liver metastases
We performed whole exome sequencing and copy number analysis for 15 triplets, each comprising normal colorectal tissue, primary colorectal carcinoma, and its synchronous matched liver metastasis. We analyzed the similarities and differences between primary colorectal carcinoma and matched liver met...
ORGANISM(S): Homo sapiens 
2014-03-01 | E-GEOD-53799 | biostudies-arrayexpress
GenomicsSCLC_SNP_6.0 - samples
SNP 6.0 arrays of small cell lung cancer
EGAD00010000558 | EGA
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