Sort   by:  
 Page size 
TranscriptomicsNFIB is a driver of SCLC initiation, progression and metastasis in mouse and marks metastatic disease in patients
Small Cell Lung Cancer (SCLC) is the most aggressive type of lung cancer with early metastatic dissemination and invariable development of resistant disease for which no effective treatment is available to date. Mouse models of SCLC based on inactivation of Rb1 and Trp53 developed earlier showed fre...
ORGANISM(S): Mus musculus 
2016-07-29 | E-GEOD-82005 | biostudies-arrayexpress
Proteomics,MultiomicsElectrophilic stress induced by itaconate and its derivatives regulates ATF3-IKBZ inflammatory axis independently of Nrf2 induction
Metabolic regulation recently emerged as a novel powerful principle guiding immune responses. The natural metabolite itaconate and its membrane permeable derivative dimethyl itaconate (DI) were recently shown to selectively inhibit a subset of cytokines during macrophage activation, yet the precise ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2018-02-25 | MSV000082101 | MassIVE
Sort   by:  
 Page size