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UnknownRandomized, Open-Label Phase II Study Evaluating the Efficacy and Safety of Talimogene Laherparepvec in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced, Unresectable Melanoma.
Not available
S-EPMC6075852 | biostudies-literature
TranscriptomicsRNA-seq of murine small intestinal organoids treated with type I PRMT inhibitor MS023 against untreated controls
Murine small intestinal organoids were cultured in the presence or absence of 5µM inhibitor MS023 (PubChem CID 92136227), which targets type I protein arginine methyltransferases Prmt1, Prmt3, Prmt4, Prmt6, Prmt8. Organoids were grown in culture media containing EGF, Noggin and R-spondin (ENR), medi...
ORGANISM(S): Mus musculus 
2020-12-16 | E-MTAB-9291 | biostudies-arrayexpress
TranscriptomicsRNA-seq of murine small intestinal organoids treated with Ep300/Crebbp inhibitor I-CBP112 against untreated controls
Murine small intestinal organoids were cultured in the presence or absence of 3µM inhibitor I-CBP112 (PubChem CID 90488984), which targets E1A Binding Protein P300 (Ep300) and Creb-binding protein (Crebbp, Cbp). Organoids were grown in culture media containing EGF, Noggin and R-spondin (ENR), media ...
ORGANISM(S): Mus musculus 
2020-12-16 | E-MTAB-9290 | biostudies-arrayexpress
UnknownFoveolar thickness as potential standardized structural outcome measurement in studies of Bietti crystalline dystrophy.
Not available
S-EPMC9424222 | biostudies-literature
UnknownA pathogenic in-frame deletion-insertion variant in BEST1 phenocopies Stargardt disease.
Not available
S-EPMC9746905 | biostudies-literature
UnknownEvaluation of human papillomavirus antibodies and risk of subsequent head and neck cancer.
Not available
S-EPMC3709056 | biostudies-literature
UnknownClinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis.
Not available
S-EPMC4030775 | biostudies-literature
UnknownA semi-automated intestinal organoid screening method demonstrates epigenetic control of epithelial maturation
Not available
ORGANISM(S): Mus musculus 
S-BSST447 | biostudies-other
TranscriptomicsFT1 and FT2 network analysis in poplar
We conducted microarray experiments by comparing constitutive and inducible Flowering Locus T1 (FT1) and FT2 constructs with appropriate controls, followed by the identification of common targets of Pro35S:FT1 and ProHSP:FT1 or Pro35S:FT2 and ProHSP:FT2. Independent samples of leaf tissues were coll...
ORGANISM(S): Populus tremula x Populus tremuloides 
2011-05-23 | E-GEOD-24609 | biostudies-arrayexpress
TranscriptomicsTime-course leaf expression data from Populus deltoides
We conducted micro-array analysis to quantify the global transcriptome variations in leaves through the course of the year allowing for identification of changing developmental signals. We used RNA samples from pre-formed and mature leaves in the upper crown of a sexually mature Populus deltoides tr...
ORGANISM(S): Populus deltoides 
2011-05-23 | E-GEOD-24349 | biostudies-arrayexpress
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