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ProteomicsTissue extracellular matrix hydrogels as alternative to Matrigel for culturing gastrointestinal organoids
Matrigel, a mouse tumor extracellular matrix (ECM) protein mixture, is an indispensable component of most organoid tissue culture. However, it has limited the utility of organoids for drug development and regenerative medicine due to its tumor-derived origin, batch-to batch variation, high cost, and...
ORGANISM(S): Sus scrofa (Pig) Mus musculus (Mouse) 
2022-02-10 | PXD023694 | Pride
Organoid Matrigel Lc-ms/ms 
ProteomicsTranscriptome and proteome analysis of the human corneal endothelium and aqueous humor reveal endothelial cell dysfunction markers
Background: The underlying mechanism as well as diagnostic molecular biomarkers for corneal endothelial cell dysfunction (CECD) remain elusive. This study aimed to elucidate molecular mechanism of CECD via proteomic and transcriptomic approaches and identify novel biomarkers in aqueous humor (AH) di...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD023772 | Pride
Proteomics Aqueous humor Corneal endothelial cell dysfunction Transcriptomics Biomarker Bullous keratopathy 
TranscriptomicsMus musculus hematopoietic stem cell
A transcriptome study in mouse hematopoietic stem cells was performed using a sensitive SAGE method, in an attempt to detect medium and low abundant transcripts expressed in these cells. Among a total of 31,380 unique transcript, 17,326 (55%) known genes were detected, 14,054 (45%) low-copy transcri...
ORGANISM(S): Mus musculus 
2009-05-20 | E-GEOD-16139 | biostudies-arrayexpress
UnknownTRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage.
Not available
S-EPMC4735692 | biostudies-literature
ProteomicsPGRC Cancer Proteome Study of Gastric Tissue
The goal of the project is to analyze different layers of proteome information including protein abundance and post-translational modifications of PGRC gastric tissue samples. Three pairs of human gastric cancer and adjacent normal tissues were extensively characterized by serial enrichments of phos...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080818 | MassIVE
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